Lipolysis defect in people with obesity who undergo metabolic surgery

Objective Cross‐sectional studies demonstrate that catecholamine stimulation of fat cell lipolysis is blunted in obesity. We investigated whether this defect persists after substantial weight loss has been induced by metabolic surgery, and whether it is related to the outcome. Design/Methods Patient...

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Veröffentlicht in:	Journal of internal medicine 2022-10, Vol.292 (4), p.667-678
Hauptverfasser:	Rydén, Mikael, Andersson, Daniel P., Kotopouli, Maria I., Stenberg, Erik, Näslund, Erik, Thorell, Anders, Sørensen, Thorkild I. A., Arner, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adrenergic receptors Bariatric Surgery Body fat Body mass Body Mass Index Body size Body Weight Body weight loss Catecholamine Catecholamines Catecholamines - pharmacology Cell size Cross-Sectional Studies Defects Gastric Bypass Gastrointestinal surgery Glycerol Hormones Humans Isoproterenol - pharmacology Lipolysis Lipolysis - physiology Metabolism Noradrenaline Norepinephrine Obesity Obesity - metabolism Obesity - surgery Obesity, Morbid - surgery Patients Receptors, Adrenergic - metabolism Roux-en-Y gastric bypass Surgery Treatment Outcome Weight control Weight loss Weight reduction
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