Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non‐Alzheimer's disease pathophysiology

Background Suspected non‐Alzheimer's disease pathophysiology (SNAP) is a biomarker concept that encompasses individuals with neuronal injury but without amyloidosis. We aim to investigate the pathophysiology of SNAP, defined as abnormal tau without amyloidosis, in individuals with mild cognitiv...

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Veröffentlicht in:	Alzheimer's & dementia 2023-03, Vol.19 (3), p.807-820
Hauptverfasser:	Delvenne, Aurore, Gobom, Johan, Tijms, Betty, Bos, Isabelle, Reus, Lianne M., Dobricic, Valerija, Kate, Mara ten, Verhey, Frans, Ramakers, Inez, Scheltens, Philip, Teunissen, Charlotte E., Vandenberghe, Rik, Schaeverbeke, Jolien, Gabel, Silvy, Popp, Julius, Peyratout, Gwendoline, Martinez‐Lage, Pablo, Tainta, Mikel, Tsolaki, Magda, Freund‐Levi, Yvonne, Lovestone, Simon, Streffer, Johannes, Barkhof, Frederik, Bertram, Lars, Blennow, Kaj, Zetterberg, Henrik, Visser, Pieter Jelle, Vos, Stephanie J. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	adult Aged Alzheimer Disease - cerebrospinal fluid Alzheimer's disease Amyloid beta-Peptides - cerebrospinal fluid biomarkers Biomarkers - cerebrospinal fluid cerebrospinal fluid Cognitive Dysfunction - cerebrospinal fluid disease pathophysiology Female Humans impairment Male Middle Aged mild cognitive mild cognitive impairment Neurologi Neurology Neurosciences & Neurology pathophysiology Peptide Fragments - cerebrospinal fluid protein Proteomics suspected non-Alzheimer's suspected non-Alzheimer's disease pathophysiology tau tau Proteins - cerebrospinal fluid
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