Haptoglobin Induces a Specific Proteomic Profile and a Mature-Associated Phenotype on Primary Human Monocyte-Derived Dendritic Cells

Damage-associated molecular patterns (DAMPs) play a critical role in dendritic cells (DCs) ability to trigger a specific and efficient adaptive immune response for different physiological and pathological scenarios. We have previously identified constitutive DAMPs (HMGB1 and Calreticulin) as well as...

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Veröffentlicht in:	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022-06, Vol.23 (13), p.6882
Hauptverfasser:	Torres, Alfredo, Vivanco, Sheilah, Lavín, Francisca, Pereda, Cristián, Chernobrovkin, Alexey, Gleisner, Alejandra, Alcota, Marcela, Larrondo, Milton, López, Mercedes N., Salazar-Onfray, Flavio, Zubarev, Roman A., González, Fermín E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity Antigens Biosynthesis Calreticulin Cancer immunotherapy Cell activation Cytokines Damage patterns Dendritic cells Flow cytometry Genotype & phenotype Haptoglobin Heat shock HMGB1 protein Immune system Immunology Immunotherapy Inflammation Lipids Lymphatic system Lymphocytes T Markers Maturation Melanoma Monocytes Peripheral blood mononuclear cells Phenotypes Proteins Proteomes Proteomics Skin cancer Stimulation
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