Hyperhomocysteinemia in acute hepatic porphyria (AHP) and implications for treatment with givosiran

Homocysteine is a sulfur-containing amino acid formed in the intermediary metabolism of methionine. Amino acid metabolism and heme biosynthesis pathways are complexly intertwined. Plasma homocysteine elevation, hyperhomocysteinemia (HHcy), has been reported in patients with acute hepatic porphyria (...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Expert review of gastroenterology & hepatology 2022-09, Vol.16 (9), p.879-894
Hauptverfasser:	Ventura, Paolo, Sardh, Eliane, Longo, Nicola, Balwani, Manisha, Plutzky, Jorge, Gouya, Laurent, Phillips, John, Rhyee, Sean, Fanelli, Mary-Jean, Sweetser, Marianne T., Petrides, Petro E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute hepatic porphyria (AHP) acute intermittent porphyria (AIP) givosiran homocysteine hyperhomocysteinemia small interfering RNA
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!