Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia

Myeloid neoplasms and acute leukemias derive from the clonal expansion of hematopoietic cells driven by somatic gene mutations. Although assessment of morphology plays a crucial role in the diagnostic evaluation of patients with these malignancies, genomic characterization has become increasingly im...

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Veröffentlicht in:	Blood 2022-11, Vol.140 (21), p.2228-2247
Hauptverfasser:	Duncavage, Eric J., Bagg, Adam, Hasserjian, Robert P., DiNardo, Courtney D., Godley, Lucy A., Iacobucci, Ilaria, Jaiswal, Siddhartha, Malcovati, Luca, Vannucchi, Alessandro M., Patel, Keyur P., Arber, Daniel A., Arcila, Maria E., Bejar, Rafael, Berliner, Nancy, Borowitz, Michael J., Branford, Susan, Brown, Anna L., Cargo, Catherine A., Döhner, Hartmut, Falini, Brunangelo, Garcia-Manero, Guillermo, Haferlach, Torsten, Hellström-Lindberg, Eva, Kim, Annette S., Klco, Jeffery M., Komrokji, Rami, Lee-Cheun Loh, Mignon, Loghavi, Sanam, Mullighan, Charles G., Ogawa, Seishi, Orazi, Attilio, Papaemmanuil, Elli, Reiter, Andreas, Ross, David M., Savona, Michael, Shimamura, Akiko, Skoda, Radek C., Solé, Francesc, Stone, Richard M., Tefferi, Ayalew, Walter, Matthew J., Wu, David, Ebert, Benjamin L., Cazzola, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical Decision-Making Genomics Hematologic Neoplasms - genetics Humans Leukemia, Myeloid, Acute - diagnosis Leukemia, Myeloid, Acute - genetics Mutation Myeloproliferative Disorders Neoplasms - genetics
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