Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death

In this randomized trial involving 84,585 participants in Poland, Norway, and Sweden, the risk of colorectal cancer at 10 years was lower among those invited to undergo screening colonoscopy than among those assigned to no screening.

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Veröffentlicht in:	The New England journal of medicine 2022-10, Vol.387 (17), p.1547-1556
Hauptverfasser:	Bretthauer, Michael, Løberg, Magnus, Wieszczy, Paulina, Kalager, Mette, Emilsson, Louise, Garborg, Kjetil, Rupinski, Maciej, Dekker, Evelien, Spaander, Manon, Bugajski, Marek, Holme, Øyvind, Zauber, Ann G., Pilonis, Nastazja D., Mroz, Andrzej, Kuipers, Ernst J., Shi, Joy, Hernán, Miguel A., Adami, Hans-Olov, Regula, Jaroslaw, Hoff, Geir, Kaminski, Michal F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Clinical Medicine Clinical Medicine General Colonic Polyps - diagnosis Colonic Polyps - epidemiology Colonic Polyps - surgery Colonoscopy Colonoscopy - adverse effects Colonoscopy - methods Colonoscopy - statistics & numerical data Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnosis Colorectal Neoplasms - epidemiology Colorectal Neoplasms - mortality Death Early Detection of Cancer - adverse effects Early Detection of Cancer - methods Early Detection of Cancer - statistics & numerical data Endoscopy Ethics Europe - epidemiology Feces Female Follow-Up Studies Gastroenterology Gastrointestinal Tract Cancer Hematology Humans Male Mass Screening - adverse effects Mass Screening - methods Mass Screening - statistics & numerical data Medical screening Middle Aged Mortality Odds Ratio Oncology Outpatient-Based Clinical Medicine Polyps Risk Statistical analysis Tumors
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Beschreibung
Zusammenfassung:	In this randomized trial involving 84,585 participants in Poland, Norway, and Sweden, the risk of colorectal cancer at 10 years was lower among those invited to undergo screening colonoscopy than among those assigned to no screening.
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa2208375