The FADS1 rs174550 Genotype Modifies the n‐3 and n‐6 PUFA and Lipid Mediator Responses to a High Alpha‐Linolenic Acid and High Linoleic Acid Diets

Scope The fatty acid composition of plasma lipids, which is associated with biomarkers and risk of non‐communicable diseases, is regulated by dietary polyunsaturated fatty acids (PUFAs) and variants of fatty acid desaturase (FADS). We investigated the interactions between dietary PUFAs and FADS1 rs1...

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Veröffentlicht in:	Molecular nutrition & food research 2022-12, Vol.66 (24), p.e2200351-n/a
Hauptverfasser:	Meuronen, Topi, Lankinen, Maria A., Kolmert, Johan, de Mello, Vanessa Derenji, Sallinen, Taisa, Ågren, Jyrki, Virtanen, Kirsi A., Laakso, Markku, Wheelock, Craig E., Pihlajamäki, Jussi, Schwab, Ursula
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Linolenic Acid Arachidonic acid Biomarkers Composition Cytochrome Cytochrome P450 Cytochromes P450 Desaturase Diet eicosanoid Eicosapentaenoic acid Epoxides FADS Fatty acid composition Fatty Acid Desaturases - genetics Fatty Acids Fatty Acids, Unsaturated Genotype Genotype & phenotype Genotypes Health risks Humans Linoleic Acid Linolenic acid Lipids Liquid chromatography Mass spectrometry Mass spectroscopy octadecanoid Plasma Polymorphism, Single Nucleotide Polyunsaturated fatty acids Prostaglandin endoperoxide synthase
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