Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants

Obesity is highly prevalent and disabling, especially in individuals with severe mental illness including bipolar disorders (BD). The brain is a target organ for both obesity and BD. Yet, we do not understand how cortical brain alterations in BD and obesity interact. We obtained body mass index (BMI...

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Veröffentlicht in:	Psychological medicine 2023-10, Vol.53 (14), p.6743-6753
Hauptverfasser:	McWhinney, Sean R., Abé, Christoph, Alda, Martin, Benedetti, Francesco, Bøen, Erlend, del Mar Bonnin, Caterina, Borgers, Tiana, Brosch, Katharina, Canales-Rodríguez, Erick J., Cannon, Dara M., Dannlowski, Udo, Diaz-Zuluaga, Ana M., Dietze, Lorielle M.F., Elvsåshagen, Torbjørn, Eyler, Lisa T., Fullerton, Janice M., Goikolea, Jose M., Goltermann, Janik, Grotegerd, Dominik, Haarman, Bartholomeus C. M., Hahn, Tim, Howells, Fleur M., Ingvar, Martin, Jahanshad, Neda, Kircher, Tilo T. J., Krug, Axel, Kuplicki, Rayus T., Landén, Mikael, Lemke, Hannah, Liberg, Benny, Lopez-Jaramillo, Carlos, Malt, Ulrik F., Martyn, Fiona M., Mazza, Elena, McDonald, Colm, McPhilemy, Genevieve, Meier, Sandra, Meinert, Susanne, Meller, Tina, Melloni, Elisa M. T., Mitchell, Philip B., Nabulsi, Leila, Nenadic, Igor, Opel, Nils, Ophoff, Roel A., Overs, Bronwyn J., Pfarr, Julia-Katharina, Pineda-Zapata, Julian A., Pomarol-Clotet, Edith, Raduà, Joaquim, Repple, Jonathan, Richter, Maike, Ringwald, Kai G., Roberts, Gloria, Ross, Alex, Salvador, Raymond, Savitz, Jonathan, Schmitt, Simon, Schofield, Peter R., Sim, Kang, Stein, Dan J., Stein, Frederike, Temmingh, Henk S., Thiel, Katharina, Thomopoulos, Sophia I., van Haren, Neeltje E. M., Vargas, Cristian, Vieta, Eduard, Vreeker, Annabel, Waltemate, Lena, Yatham, Lakshmi N., Ching, Christopher R. K., Andreassen, Ole A., Thompson, Paul M., Hajek, Tomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anatomy Antipsychotics Bipolar disorder Bipolar Disorder - diagnostic imaging Bipolar Disorder - pathology Body Mass Index Brain architecture Brain structure Cerebral Cortex - diagnostic imaging Cerebral Cortex - pathology Cognitive ability Drug abuse Drugs Female Humans Magnetic Resonance Imaging Male Mathematical models Medical imaging Mental disorders Middle Aged Morphology Neuroimaging Obesity Obesity - pathology Original Original Article Overweight Post traumatic stress disorder Psychiatry Psychotropic drugs Psykiatri Surface area Working groups
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