Quality assurance in human papillomavirus testing for primary cervical screening

The recommendation for cervical screening is that it should be based on human papillomavirus (HPV) molecular testing. For all screening programs, attention to quality assurance is required to fully realize the benefits. Internationally recognized quality assurance recommendations for HPV-based scree...

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Veröffentlicht in:International journal of gynecological cancer 2023-05, Vol.33 (5), p.802-811
Hauptverfasser: Cuschieri, Kate, Fellner, María Dolores, Arroyo Mühr, Laila Sara, Padalko, Elizaveta, Correa, Rita Mariel, Dillner, Joakim, Gultekin, Murat, Picconi, Maria Alejandra
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container_end_page 811
container_issue 5
container_start_page 802
container_title International journal of gynecological cancer
container_volume 33
creator Cuschieri, Kate
Fellner, María Dolores
Arroyo Mühr, Laila Sara
Padalko, Elizaveta
Correa, Rita Mariel
Dillner, Joakim
Gultekin, Murat
Picconi, Maria Alejandra
description The recommendation for cervical screening is that it should be based on human papillomavirus (HPV) molecular testing. For all screening programs, attention to quality assurance is required to fully realize the benefits. Internationally recognized quality assurance recommendations for HPV-based screening are needed that are ideally applicable for a variety of settings, including in low- and middle-income countries. We summarize the main points of quality assurance for HPV screening, with a focus on the selection, implementation, and use of an HPV screening test, quality assurance systems (including internal quality control and external quality assessment), and staff competence. While we recognize that it might not be possible to fulfill all points in all settings, an awareness of the issues is essential.
doi_str_mv 10.1136/ijgc-2022-004197
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subjects Cellular biology
Cervical Cancer
Cervix Uteri
Early Detection of Cancer
FDA approval
Female
Genetic testing
Human papillomavirus
Human Papillomavirus Viruses
Humans
Infections
Laboratories
Mass Screening
Medical screening
Papillomaviridae
Papillomavirus Infections
Public health
Quality control
Quality standards
Reproducibility
Review
Uterine Cervical Neoplasms - diagnosis
Vaccines
Vaginal Smears
Viral infections
title Quality assurance in human papillomavirus testing for primary cervical screening
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