Naturally occurring dipeptide from elite controllers with dual anti-HIV-1 mechanism

•WG-am is a naturally occurring dipeptide from elite controllers with anti-HIV activity.•WG-am is a new antiviral compound with two independent mechanisms of action against HIV.•WG-am binds to gp120 CD4 binding pocket and blocks the binding between HIV-1 and the host cell.•WG-am also exerts a post-e...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of antimicrobial agents 2023-05, Vol.61 (5), p.106792-106792, Article 106792
Hauptverfasser:	Ceña-Diez, Rafael, Narayanan, Aswathy, Ray, Shilpa, van de Klundert, Maarten, Rodriguez, Jimmy E, Nilvebrant, Johan, Nygren, Per-Åke, Végvári, Ákos, van Domselaar, Robert, Sönnerborg, Anders
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Antiviral Agents Dipeptides Dual mechanism Elite Controllers Entry HIV HIV Infections - drug therapy HIV-1 Humans Medicin och hälsovetenskap Proteomics Retrotranscription Therapy Virus Replication
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!