5hmC Immunohistochemistry: A Predictor of TERT Promoter Mutational Status in Follicular Thyroid Carcinoma?

Telomerase reverse transcriptase (TERT) gene aberrancies correlate to adverse prognosis in follicular thyroid carcinoma (FTC). As loss of 5-hydroxymethylcytosine (5hmC) has been associated with TERT promoter mutations in papillary thyroid carcinoma, this study sought to analyze the levels of 5hmC in...

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Veröffentlicht in:	The journal of histochemistry and cytochemistry 2023-08, Vol.71 (8), p.451-458
Hauptverfasser:	Hysek, Martin, Hellgren, Samuel L., Condello, Vincenzo, Xu, Yiyi, Larsson, Catharina, Zedenius, Jan, Juhlin, C. Christofer
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Follicular - diagnosis Adenocarcinoma, Follicular - genetics Adenocarcinoma, Follicular - pathology Humans Immunohistochemistry Medicin och hälsovetenskap Mutation Telomerase - genetics Thyroid Cancer, Papillary Thyroid Neoplasms - diagnosis Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology
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