Studies on the Regulation and Localization of 5‐Lipoxygenase in Human B‐Lymphocytes

Stimulated B‐lymphocytes, isolated from patients with chronic lymphocytic leukemia of B‐cell type (B‐CLL cells) or from human tonsils, produced similar amounts of leukotriene (LT) B4 and 5–hydroxy‐eicosatetraenoic acid (5‐HETE) as polymorphonuclear granulocytes. Unlike intact granulocytes or monocyt...

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Veröffentlicht in:	European journal of biochemistry 1995-08, Vol.232 (1), p.37-46
Hauptverfasser:	Jakobsson, Per‐Johan, Shaskin, Pavel, Larsson, Pontus, Feltenmark, Stina, Odlander, Björn, Aguilar‐Santelises, Miguel, Jondal, Mikael, Biberfeld, Peter, Claesson, Hans‐Erik
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Lipoxygenase-Activating Proteins 5‐lipoxygenase‐activating protein Arachidonate 5-Lipoxygenase - metabolism arachidonic acid B-Lymphocytes - enzymology Base Sequence BWHAC Carrier Proteins - biosynthesis Cell Nucleus - metabolism Humans Immunohistochemistry Indoles - pharmacology leukotriene Membrane Proteins - biosynthesis MK‐886 Molecular Sequence Data Polymerase Chain Reaction Sulfhydryl Reagents - pharmacology
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