A high-density YAC contig map of human chromosome 22

We have constructed a high-resolution clone map of human chromosome 22 which integrates the available physical and genetic information, establishing a single consensus. The map consists of all classes of DNA landmarks ordered on 705 yeast artificial chromosomes (YACs) at an average landmark density...

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Veröffentlicht in:	Nature (London) 1995-09, Vol.377 (6547 Suppl), p.367-367
Hauptverfasser:	Collins, J E, Cole, C G, Smink, L J, Garrett, C L, Leversha, M A, Soderlund, C A, Maslen, G L, Everett, L A, Rice, K M, Coffey, A J
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosome Mapping - methods Chromosomes Chromosomes, Artificial, Yeast Chromosomes, Human, Pair 22 Clones Deoxyribonucleic acid DNA Genes Genetic Markers Genetics Humans Medicin och hälsovetenskap Molecular biology Sequence Tagged Sites Yeast Yeasts
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Beschreibung
Zusammenfassung:	We have constructed a high-resolution clone map of human chromosome 22 which integrates the available physical and genetic information, establishing a single consensus. The map consists of all classes of DNA landmarks ordered on 705 yeast artificial chromosomes (YACs) at an average landmark density of more than one per 70 kilobases. This map represents the practical limits of currently available YAC resources and provides the basis for determination of the entire gene content and genomic DNA sequence of human chromosome 22.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/377367a0