The Duration of Oral Anticoagulant Therapy after a Second Episode of Venous Thromboembolism
Oral anticoagulant therapy is routinely given to most patients who have had episodes of venous thromboembolism. Two recent multicenter trials have demonstrated that if the duration of treatment after a first episode of thromboembolism is extended to three to six months, instead of four to six weeks,...
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Veröffentlicht in: | The New England journal of medicine 1997-02, Vol.336 (6), p.393-398 |
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container_title | The New England journal of medicine |
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creator | Schulman, Sam Granqvist, Staffan Holmström, Margareta Carlsson, Anders Lindmarker, Per Nicol, Peter Eklund, Sven-Gunnar Nordlander, Sune Lärfars, Gerd Leijd, Barbro Linder, Olle Loogna, Enno Walter, Hans Viering, Stanka Hjorth, Martin Boberg, Jonas |
description | Oral anticoagulant therapy is routinely given to most patients who have had episodes of venous thromboembolism. Two recent multicenter trials have demonstrated that if the duration of treatment after a first episode of thromboembolism is extended to three to six months, instead of four to six weeks, the rate of recurrence can be reduced, especially among patients with permanent risk factors such as thromboembolism that was idiopathic in nature and venous insufficiency.
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The optimal duration of secondary prophylaxis after a second episode of venous thromboembolism is unknown. In one study, patients were stratified according to whether the episode of . . . |
doi_str_mv | 10.1056/NEJM199702063360601 |
format | Article |
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The optimal duration of secondary prophylaxis after a second episode of venous thromboembolism is unknown. In one study, patients were stratified according to whether the episode of . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199702063360601</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Biological and medical sciences ; Blood. Blood coagulation. Reticuloendothelial system ; Cardiovascular disease ; Drug therapy ; Medical sciences ; Pharmacology. Drug treatments</subject><ispartof>The New England journal of medicine, 1997-02, Vol.336 (6), p.393-398</ispartof><rights>Copyright © 1997 Massachusetts Medical Society. All rights reserved.</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c575t-16add7f8036ba226c6cc1249c747518b7140f2f8363463175316ab2971f6c8833</citedby><cites>FETCH-LOGICAL-c575t-16add7f8036ba226c6cc1249c747518b7140f2f8363463175316ab2971f6c8833</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199702063360601$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM199702063360601$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>230,314,776,780,881,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2563911$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:1937955$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Schulman, Sam</creatorcontrib><creatorcontrib>Granqvist, Staffan</creatorcontrib><creatorcontrib>Holmström, Margareta</creatorcontrib><creatorcontrib>Carlsson, Anders</creatorcontrib><creatorcontrib>Lindmarker, Per</creatorcontrib><creatorcontrib>Nicol, Peter</creatorcontrib><creatorcontrib>Eklund, Sven-Gunnar</creatorcontrib><creatorcontrib>Nordlander, Sune</creatorcontrib><creatorcontrib>Lärfars, Gerd</creatorcontrib><creatorcontrib>Leijd, Barbro</creatorcontrib><creatorcontrib>Linder, Olle</creatorcontrib><creatorcontrib>Loogna, Enno</creatorcontrib><creatorcontrib>Walter, Hans</creatorcontrib><creatorcontrib>Viering, Stanka</creatorcontrib><creatorcontrib>Hjorth, Martin</creatorcontrib><creatorcontrib>Boberg, Jonas</creatorcontrib><creatorcontrib>the Duration of Anticoagulation Trial Study Group</creatorcontrib><title>The Duration of Oral Anticoagulant Therapy after a Second Episode of Venous Thromboembolism</title><title>The New England journal of medicine</title><description>Oral anticoagulant therapy is routinely given to most patients who have had episodes of venous thromboembolism. Two recent multicenter trials have demonstrated that if the duration of treatment after a first episode of thromboembolism is extended to three to six months, instead of four to six weeks, the rate of recurrence can be reduced, especially among patients with permanent risk factors such as thromboembolism that was idiopathic in nature and venous insufficiency.
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The optimal duration of secondary prophylaxis after a second episode of venous thromboembolism is unknown. In one study, patients were stratified according to whether the episode of . . .</description><subject>Biological and medical sciences</subject><subject>Blood. Blood coagulation. Reticuloendothelial system</subject><subject>Cardiovascular disease</subject><subject>Drug therapy</subject><subject>Medical sciences</subject><subject>Pharmacology. 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Blood coagulation. Reticuloendothelial system</topic><topic>Cardiovascular disease</topic><topic>Drug therapy</topic><topic>Medical sciences</topic><topic>Pharmacology. 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Two recent multicenter trials have demonstrated that if the duration of treatment after a first episode of thromboembolism is extended to three to six months, instead of four to six weeks, the rate of recurrence can be reduced, especially among patients with permanent risk factors such as thromboembolism that was idiopathic in nature and venous insufficiency.
1
,
2
The optimal duration of secondary prophylaxis after a second episode of venous thromboembolism is unknown. In one study, patients were stratified according to whether the episode of . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><doi>10.1056/NEJM199702063360601</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
subjects | Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Cardiovascular disease Drug therapy Medical sciences Pharmacology. Drug treatments |
title | The Duration of Oral Anticoagulant Therapy after a Second Episode of Venous Thromboembolism |
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