The Duration of Oral Anticoagulant Therapy after a Second Episode of Venous Thromboembolism

Oral anticoagulant therapy is routinely given to most patients who have had episodes of venous thromboembolism. Two recent multicenter trials have demonstrated that if the duration of treatment after a first episode of thromboembolism is extended to three to six months, instead of four to six weeks,...

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Veröffentlicht in:The New England journal of medicine 1997-02, Vol.336 (6), p.393-398
Hauptverfasser: Schulman, Sam, Granqvist, Staffan, Holmström, Margareta, Carlsson, Anders, Lindmarker, Per, Nicol, Peter, Eklund, Sven-Gunnar, Nordlander, Sune, Lärfars, Gerd, Leijd, Barbro, Linder, Olle, Loogna, Enno, Walter, Hans, Viering, Stanka, Hjorth, Martin, Boberg, Jonas
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container_end_page 398
container_issue 6
container_start_page 393
container_title The New England journal of medicine
container_volume 336
creator Schulman, Sam
Granqvist, Staffan
Holmström, Margareta
Carlsson, Anders
Lindmarker, Per
Nicol, Peter
Eklund, Sven-Gunnar
Nordlander, Sune
Lärfars, Gerd
Leijd, Barbro
Linder, Olle
Loogna, Enno
Walter, Hans
Viering, Stanka
Hjorth, Martin
Boberg, Jonas
description Oral anticoagulant therapy is routinely given to most patients who have had episodes of venous thromboembolism. Two recent multicenter trials have demonstrated that if the duration of treatment after a first episode of thromboembolism is extended to three to six months, instead of four to six weeks, the rate of recurrence can be reduced, especially among patients with permanent risk factors such as thromboembolism that was idiopathic in nature and venous insufficiency. 1 , 2 The optimal duration of secondary prophylaxis after a second episode of venous thromboembolism is unknown. In one study, patients were stratified according to whether the episode of . . .
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subjects Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Cardiovascular disease
Drug therapy
Medical sciences
Pharmacology. Drug treatments
title The Duration of Oral Anticoagulant Therapy after a Second Episode of Venous Thromboembolism
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