Idiotype‐specific T lymphocytes in monoclonal gammopathies: evidence for the presence of CD4+ and CD8+ subsets

Tumour‐specific CD4+ T helper (Th) and CD8+ T cytotoxic (Tc) cells may participate in the control and eradication of tumour cells. In the present study, idiotype‐specific stimulation of CD4+ and CD8+ blood T cells from patients with monoclonal gammopathy of undetermined significance and patients wit...

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Veröffentlicht in:	British journal of haematology 1997-02, Vol.96 (2), p.338-345
Hauptverfasser:	YI, QING, ERIKSSON, INGRID, HE, WEN, HOLM, GO¨RAN, MELLSTEDT, HÅKAN, O¨STERBORG, ANDERS
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Biological and medical sciences CD4+ T cells CD4-CD8 Ratio CD4-Positive T-Lymphocytes - immunology CD8+ T cells CD8-Positive T-Lymphocytes - immunology Humans idiotype Immunodeficiencies. Immunoglobulinopathies Immunoglobulin Fab Fragments - immunology Immunoglobulinopathies Immunopathology Interferon-gamma - biosynthesis Medical sciences monoclonal gammopathies M‐component Paraproteinemias - immunology T-Lymphocyte Subsets - immunology
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