Post-hypoxic hypothermia reduces cerebrocortical release of NO and excitotoxins

HYPOTHERMIA applied after hypoxia offers neuroprotection in neonatal animals, but the mechanisms involved remain unknown. Hypoxia was induced in newborn piglets and changes in excitatory amino acids (EAAs) and the citrulline:arginine ratio (CAR) were followed by microdialysis for 5 h. After the 45 m...

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Veröffentlicht in:	Neuroreport 1997-10, Vol.8 (15), p.3359-3362
Hauptverfasser:	Thoresen, Marianne, Satas, Saulius, Puka-Sundvall, Malgorzata, Whitelaw, Andrew, Hallström, Åse, Løberg, Else-Marit, Ungerstedt, Urban, Steen, Petter Andreas, Hagberg, Henrik
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine - metabolism Biochemistry and metabolism Biological and medical sciences Central nervous system Cerebral Cortex - metabolism Citrulline - metabolism Electroencephalography Excitatory Amino Acids - metabolism Fundamental and applied biological sciences. Psychology Hypothermia - metabolism Hypoxia, Brain - metabolism Medicin och hälsovetenskap Microdialysis Nitric Oxide - metabolism Swine Vertebrates: nervous system and sense organs
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