Effects of cell density and trichostatin A on the expression of HDAC1 and p57Kip2 in Hep 3B cells

The interplay between the acetylation and deacetylation activities within the cell has been postulated to be a mechanism by which the cell regulates expression from genes at the level of chromatin. We have examined the expression pattern of the human histone deacetylase gene HDAC1 and the cyclin dep...

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Veröffentlicht in:	Biochemical and biophysical research communications 1998-04, Vol.245 (2), p.423-427
Hauptverfasser:	Gray, S G, Ekström, T J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Count Cell Division - genetics Cyclin-Dependent Kinase Inhibitor p57 Down-Regulation - physiology Enzyme Inhibitors - pharmacology Gene Expression Regulation, Neoplastic - genetics Histone Deacetylase 1 Histone Deacetylase Inhibitors Histone Deacetylases - metabolism Humans Hydroxamic Acids - pharmacology Infant, Newborn Nuclear Proteins - antagonists & inhibitors Nuclear Proteins - metabolism RNA, Messenger - metabolism Tumor Cells, Cultured
Online-Zugang:	Volltext
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