Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein

Schmallenberg virus (SBV) is a member of the Orthobunyavirus genus (Bunyaviridae family) causing malformations and abortions in ruminants. Although, as for other members of this family/genus, the non-structural protein NSs has been shown to be an interferon antagonist, very little is known regarding...

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Veröffentlicht in:	BMC genomics 2015-04, Vol.16 (1), p.324-324, Article 324
Hauptverfasser:	Blomström, Anne-Lie, Gu, Quan, Barry, Gerald, Wilkie, Gavin, Skelton, Jessica K, Baird, Margaret, McFarlane, Melanie, Schnettler, Esther, Elliott, Richard M, Palmarini, Massimo, Kohl, Alain
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - cytology Aorta - metabolism Bunyaviridae Infections - genetics Bunyaviridae Infections - virology Cattle Cells, Cultured Comparative analysis Genes Genetic aspects Genomics Health aspects Immunity, Innate Lassa fever Orthobunyavirus - isolation & purification Orthobunyavirus - metabolism Orthobunyavirus - physiology Pathobiology Patobiologi Real-Time Polymerase Chain Reaction Sequence Analysis, RNA Transcriptome Up-Regulation Viral Nonstructural Proteins - genetics Viral Nonstructural Proteins - metabolism
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