Effects of agro based organic amendments on growth and cadmium uptake in wheat and rice crops irrigated with raw city effluents: Three years field study

Cadmium (Cd) accumulates in the vegetative tissues of rice and wheat crops, posing a serious threat in the food chain. A long-term field experiment was conducted to investigate the effects of rice husk biochar (RHB), farm manure (FM), press mud (PrM), and poultry manure (PM) on the growth, yield, an...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Environmental pollution (1987) 2024-03, Vol.344, p.123365-123365, Article 123365
Hauptverfasser: Shaghaleh, Hiba, Azhar, Muhammad, Zia-ur-Rehman, Muhammad, Alhaj Hamoud, Yousef, Adam Hamad, Ammar Ali, Usman, Muhammad, Rizwan, Muhammad, Yong, Jean Wan Hong, Alharby, Hesham F., Al-Ghamdi, Abdullah G., Alharbi, Basmah M.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 123365
container_issue
container_start_page 123365
container_title Environmental pollution (1987)
container_volume 344
creator Shaghaleh, Hiba
Azhar, Muhammad
Zia-ur-Rehman, Muhammad
Alhaj Hamoud, Yousef
Adam Hamad, Ammar Ali
Usman, Muhammad
Rizwan, Muhammad
Yong, Jean Wan Hong
Alharby, Hesham F.
Al-Ghamdi, Abdullah G.
Alharbi, Basmah M.
description Cadmium (Cd) accumulates in the vegetative tissues of rice and wheat crops, posing a serious threat in the food chain. A long-term field experiment was conducted to investigate the effects of rice husk biochar (RHB), farm manure (FM), press mud (PrM), and poultry manure (PM) on the growth, yield, and economics of wheat and rice crops grown with sewage water. The results showed that RHB increased wheat plant height (27%, 66%, 70%), spike-length (33%, 99%, 56%), straw yield (21%, 51%, 49%), and grain yield (42%, 63%, 65%) in year-1, year-2, and year-3, than respective controls. For rice crop, RHB showed the maximum increase in plant height (64%, 92%, 96%), spike length (55%, 95%, 90%), straw yield (34%, 53%, 55%), and grain yield (46%, 66%, 69%) each year (2019–2021), compared to their respective controls. The Cd immobilization was increased by the application of RHB while other treatments followed FM > PrM > PM > control in each year of wheat and rice crops. For year-1, benefit-cost ratio remained maximum with the application of FM while for the 2nd and 3rd years in sequence, RHB proved more economical than other treatments and consistently produced wheat and rice with lower Cd concentration than FM, PrM, and PM in grains. This long-term experiment suggested that the application of organic amendments consistently increased biomass of rice and wheat and decreased the Cd concentration in tissues. The RHB remained more effective compared with FM, PrM, and PM in terms of yield, low Cd accumulation and economics of rice and wheat crops. [Display omitted] •Organic amendments enhanced wheat and rice yield under Cd stress.•Amendments differentially affected Cd availability in soil and plant uptake.•Farm manure was more effective in reducing Cd uptake by crops in 1st year.•RHB was more effective in reducing Cd uptake by crops in 2nd and 3rd year.
doi_str_mv 10.1016/j.envpol.2024.123365
format Article
fullrecord <record><control><sourceid>proquest_swepu</sourceid><recordid>TN_cdi_swepub_primary_oai_slubar_slu_se_127949</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0269749124000794</els_id><sourcerecordid>2918509753</sourcerecordid><originalsourceid>FETCH-LOGICAL-c447t-3a80d362f1af131bc09cb423a0f6dc9a76c8ac189c1490525e27cd35980558883</originalsourceid><addsrcrecordid>eNp9kctuFDEQRVsIRIbAHyDkJZuZ-NXdNgskFIWHFIlNWFvVdnnGQ7-wu9OaP8nn4qFDllmUalH33irVKYr3jO4YZdXVcYf9_Ti0O0653DEuRFW-KDZM1WJbSS5fFhvKK72tpWYXxZuUjpRSKYR4XVwIxUWtSrEpHm68RzslMngC-ziQBhI6MsQ99MES6LB3uc6CnuT5Mh0I9I5YcF2YOzKPE_xGEnqyHBCmf7MYLBIbhzGREGPYw5QTl5CdERZiw3Qi6H07n2M_kbtDRCQnhJiID9g6kqbZnd4Wrzy0Cd899svi19ebu-vv29uf335cf7ndWinraStAUScq7hl4JlhjqbaN5AKor5zVUFdWgWVKWyY1LXmJvLZOlFrRslRKictit-amBce5MWMMHcSTGSCY1M4NxHMzCQ3jtZY6Gz6uhjEOf2ZMk-lCsti20OMwJ8M1UyXVdSmyVK7S_IyUIvqndEbNGaI5mhWiOUM0K8Rs-_C4YW46dE-m_9Sy4PMqwPyY-4D5RBuwt-hCzDCNG8LzG_4CSTayLw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2918509753</pqid></control><display><type>article</type><title>Effects of agro based organic amendments on growth and cadmium uptake in wheat and rice crops irrigated with raw city effluents: Three years field study</title><source>Elsevier ScienceDirect Journals</source><source>SWEPUB Freely available online</source><creator>Shaghaleh, Hiba ; Azhar, Muhammad ; Zia-ur-Rehman, Muhammad ; Alhaj Hamoud, Yousef ; Adam Hamad, Ammar Ali ; Usman, Muhammad ; Rizwan, Muhammad ; Yong, Jean Wan Hong ; Alharby, Hesham F. ; Al-Ghamdi, Abdullah G. ; Alharbi, Basmah M.</creator><creatorcontrib>Shaghaleh, Hiba ; Azhar, Muhammad ; Zia-ur-Rehman, Muhammad ; Alhaj Hamoud, Yousef ; Adam Hamad, Ammar Ali ; Usman, Muhammad ; Rizwan, Muhammad ; Yong, Jean Wan Hong ; Alharby, Hesham F. ; Al-Ghamdi, Abdullah G. ; Alharbi, Basmah M. ; Sveriges lantbruksuniversitet</creatorcontrib><description>Cadmium (Cd) accumulates in the vegetative tissues of rice and wheat crops, posing a serious threat in the food chain. A long-term field experiment was conducted to investigate the effects of rice husk biochar (RHB), farm manure (FM), press mud (PrM), and poultry manure (PM) on the growth, yield, and economics of wheat and rice crops grown with sewage water. The results showed that RHB increased wheat plant height (27%, 66%, 70%), spike-length (33%, 99%, 56%), straw yield (21%, 51%, 49%), and grain yield (42%, 63%, 65%) in year-1, year-2, and year-3, than respective controls. For rice crop, RHB showed the maximum increase in plant height (64%, 92%, 96%), spike length (55%, 95%, 90%), straw yield (34%, 53%, 55%), and grain yield (46%, 66%, 69%) each year (2019–2021), compared to their respective controls. The Cd immobilization was increased by the application of RHB while other treatments followed FM &gt; PrM &gt; PM &gt; control in each year of wheat and rice crops. For year-1, benefit-cost ratio remained maximum with the application of FM while for the 2nd and 3rd years in sequence, RHB proved more economical than other treatments and consistently produced wheat and rice with lower Cd concentration than FM, PrM, and PM in grains. This long-term experiment suggested that the application of organic amendments consistently increased biomass of rice and wheat and decreased the Cd concentration in tissues. The RHB remained more effective compared with FM, PrM, and PM in terms of yield, low Cd accumulation and economics of rice and wheat crops. [Display omitted] •Organic amendments enhanced wheat and rice yield under Cd stress.•Amendments differentially affected Cd availability in soil and plant uptake.•Farm manure was more effective in reducing Cd uptake by crops in 1st year.•RHB was more effective in reducing Cd uptake by crops in 2nd and 3rd year.</description><identifier>ISSN: 0269-7491</identifier><identifier>ISSN: 1873-6424</identifier><identifier>EISSN: 1873-6424</identifier><identifier>DOI: 10.1016/j.envpol.2024.123365</identifier><identifier>PMID: 38237853</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Agricultural Science ; Benefit-cost ratio ; Cadmium ; Environmental Sciences related to Agriculture and Land-use ; Farm manure ; Grain yield ; Immobilization ; Jordbruksvetenskap ; Miljö- och naturvårdsvetenskap ; Rice husk biochar</subject><ispartof>Environmental pollution (1987), 2024-03, Vol.344, p.123365-123365, Article 123365</ispartof><rights>2024 The Authors</rights><rights>Copyright © 2024. Published by Elsevier Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c447t-3a80d362f1af131bc09cb423a0f6dc9a76c8ac189c1490525e27cd35980558883</citedby><cites>FETCH-LOGICAL-c447t-3a80d362f1af131bc09cb423a0f6dc9a76c8ac189c1490525e27cd35980558883</cites><orcidid>0000-0003-3325-8254 ; 0000-0002-3513-2041 ; 0000-0002-9513-1729 ; 0000-0001-8804-3790 ; 0000-0003-0945-9224</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0269749124000794$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,550,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38237853$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://res.slu.se/id/publ/127949$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Shaghaleh, Hiba</creatorcontrib><creatorcontrib>Azhar, Muhammad</creatorcontrib><creatorcontrib>Zia-ur-Rehman, Muhammad</creatorcontrib><creatorcontrib>Alhaj Hamoud, Yousef</creatorcontrib><creatorcontrib>Adam Hamad, Ammar Ali</creatorcontrib><creatorcontrib>Usman, Muhammad</creatorcontrib><creatorcontrib>Rizwan, Muhammad</creatorcontrib><creatorcontrib>Yong, Jean Wan Hong</creatorcontrib><creatorcontrib>Alharby, Hesham F.</creatorcontrib><creatorcontrib>Al-Ghamdi, Abdullah G.</creatorcontrib><creatorcontrib>Alharbi, Basmah M.</creatorcontrib><creatorcontrib>Sveriges lantbruksuniversitet</creatorcontrib><title>Effects of agro based organic amendments on growth and cadmium uptake in wheat and rice crops irrigated with raw city effluents: Three years field study</title><title>Environmental pollution (1987)</title><addtitle>Environ Pollut</addtitle><description>Cadmium (Cd) accumulates in the vegetative tissues of rice and wheat crops, posing a serious threat in the food chain. A long-term field experiment was conducted to investigate the effects of rice husk biochar (RHB), farm manure (FM), press mud (PrM), and poultry manure (PM) on the growth, yield, and economics of wheat and rice crops grown with sewage water. The results showed that RHB increased wheat plant height (27%, 66%, 70%), spike-length (33%, 99%, 56%), straw yield (21%, 51%, 49%), and grain yield (42%, 63%, 65%) in year-1, year-2, and year-3, than respective controls. For rice crop, RHB showed the maximum increase in plant height (64%, 92%, 96%), spike length (55%, 95%, 90%), straw yield (34%, 53%, 55%), and grain yield (46%, 66%, 69%) each year (2019–2021), compared to their respective controls. The Cd immobilization was increased by the application of RHB while other treatments followed FM &gt; PrM &gt; PM &gt; control in each year of wheat and rice crops. For year-1, benefit-cost ratio remained maximum with the application of FM while for the 2nd and 3rd years in sequence, RHB proved more economical than other treatments and consistently produced wheat and rice with lower Cd concentration than FM, PrM, and PM in grains. This long-term experiment suggested that the application of organic amendments consistently increased biomass of rice and wheat and decreased the Cd concentration in tissues. The RHB remained more effective compared with FM, PrM, and PM in terms of yield, low Cd accumulation and economics of rice and wheat crops. [Display omitted] •Organic amendments enhanced wheat and rice yield under Cd stress.•Amendments differentially affected Cd availability in soil and plant uptake.•Farm manure was more effective in reducing Cd uptake by crops in 1st year.•RHB was more effective in reducing Cd uptake by crops in 2nd and 3rd year.</description><subject>Agricultural Science</subject><subject>Benefit-cost ratio</subject><subject>Cadmium</subject><subject>Environmental Sciences related to Agriculture and Land-use</subject><subject>Farm manure</subject><subject>Grain yield</subject><subject>Immobilization</subject><subject>Jordbruksvetenskap</subject><subject>Miljö- och naturvårdsvetenskap</subject><subject>Rice husk biochar</subject><issn>0269-7491</issn><issn>1873-6424</issn><issn>1873-6424</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>D8T</sourceid><recordid>eNp9kctuFDEQRVsIRIbAHyDkJZuZ-NXdNgskFIWHFIlNWFvVdnnGQ7-wu9OaP8nn4qFDllmUalH33irVKYr3jO4YZdXVcYf9_Ti0O0653DEuRFW-KDZM1WJbSS5fFhvKK72tpWYXxZuUjpRSKYR4XVwIxUWtSrEpHm68RzslMngC-ziQBhI6MsQ99MES6LB3uc6CnuT5Mh0I9I5YcF2YOzKPE_xGEnqyHBCmf7MYLBIbhzGREGPYw5QTl5CdERZiw3Qi6H07n2M_kbtDRCQnhJiID9g6kqbZnd4Wrzy0Cd899svi19ebu-vv29uf335cf7ndWinraStAUScq7hl4JlhjqbaN5AKor5zVUFdWgWVKWyY1LXmJvLZOlFrRslRKictit-amBce5MWMMHcSTGSCY1M4NxHMzCQ3jtZY6Gz6uhjEOf2ZMk-lCsti20OMwJ8M1UyXVdSmyVK7S_IyUIvqndEbNGaI5mhWiOUM0K8Rs-_C4YW46dE-m_9Sy4PMqwPyY-4D5RBuwt-hCzDCNG8LzG_4CSTayLw</recordid><startdate>20240301</startdate><enddate>20240301</enddate><creator>Shaghaleh, Hiba</creator><creator>Azhar, Muhammad</creator><creator>Zia-ur-Rehman, Muhammad</creator><creator>Alhaj Hamoud, Yousef</creator><creator>Adam Hamad, Ammar Ali</creator><creator>Usman, Muhammad</creator><creator>Rizwan, Muhammad</creator><creator>Yong, Jean Wan Hong</creator><creator>Alharby, Hesham F.</creator><creator>Al-Ghamdi, Abdullah G.</creator><creator>Alharbi, Basmah M.</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>D8T</scope><scope>ZZAVC</scope><orcidid>https://orcid.org/0000-0003-3325-8254</orcidid><orcidid>https://orcid.org/0000-0002-3513-2041</orcidid><orcidid>https://orcid.org/0000-0002-9513-1729</orcidid><orcidid>https://orcid.org/0000-0001-8804-3790</orcidid><orcidid>https://orcid.org/0000-0003-0945-9224</orcidid></search><sort><creationdate>20240301</creationdate><title>Effects of agro based organic amendments on growth and cadmium uptake in wheat and rice crops irrigated with raw city effluents: Three years field study</title><author>Shaghaleh, Hiba ; Azhar, Muhammad ; Zia-ur-Rehman, Muhammad ; Alhaj Hamoud, Yousef ; Adam Hamad, Ammar Ali ; Usman, Muhammad ; Rizwan, Muhammad ; Yong, Jean Wan Hong ; Alharby, Hesham F. ; Al-Ghamdi, Abdullah G. ; Alharbi, Basmah M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c447t-3a80d362f1af131bc09cb423a0f6dc9a76c8ac189c1490525e27cd35980558883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Agricultural Science</topic><topic>Benefit-cost ratio</topic><topic>Cadmium</topic><topic>Environmental Sciences related to Agriculture and Land-use</topic><topic>Farm manure</topic><topic>Grain yield</topic><topic>Immobilization</topic><topic>Jordbruksvetenskap</topic><topic>Miljö- och naturvårdsvetenskap</topic><topic>Rice husk biochar</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shaghaleh, Hiba</creatorcontrib><creatorcontrib>Azhar, Muhammad</creatorcontrib><creatorcontrib>Zia-ur-Rehman, Muhammad</creatorcontrib><creatorcontrib>Alhaj Hamoud, Yousef</creatorcontrib><creatorcontrib>Adam Hamad, Ammar Ali</creatorcontrib><creatorcontrib>Usman, Muhammad</creatorcontrib><creatorcontrib>Rizwan, Muhammad</creatorcontrib><creatorcontrib>Yong, Jean Wan Hong</creatorcontrib><creatorcontrib>Alharby, Hesham F.</creatorcontrib><creatorcontrib>Al-Ghamdi, Abdullah G.</creatorcontrib><creatorcontrib>Alharbi, Basmah M.</creatorcontrib><creatorcontrib>Sveriges lantbruksuniversitet</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Freely available online</collection><collection>SwePub Articles full text</collection><jtitle>Environmental pollution (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shaghaleh, Hiba</au><au>Azhar, Muhammad</au><au>Zia-ur-Rehman, Muhammad</au><au>Alhaj Hamoud, Yousef</au><au>Adam Hamad, Ammar Ali</au><au>Usman, Muhammad</au><au>Rizwan, Muhammad</au><au>Yong, Jean Wan Hong</au><au>Alharby, Hesham F.</au><au>Al-Ghamdi, Abdullah G.</au><au>Alharbi, Basmah M.</au><aucorp>Sveriges lantbruksuniversitet</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of agro based organic amendments on growth and cadmium uptake in wheat and rice crops irrigated with raw city effluents: Three years field study</atitle><jtitle>Environmental pollution (1987)</jtitle><addtitle>Environ Pollut</addtitle><date>2024-03-01</date><risdate>2024</risdate><volume>344</volume><spage>123365</spage><epage>123365</epage><pages>123365-123365</pages><artnum>123365</artnum><issn>0269-7491</issn><issn>1873-6424</issn><eissn>1873-6424</eissn><abstract>Cadmium (Cd) accumulates in the vegetative tissues of rice and wheat crops, posing a serious threat in the food chain. A long-term field experiment was conducted to investigate the effects of rice husk biochar (RHB), farm manure (FM), press mud (PrM), and poultry manure (PM) on the growth, yield, and economics of wheat and rice crops grown with sewage water. The results showed that RHB increased wheat plant height (27%, 66%, 70%), spike-length (33%, 99%, 56%), straw yield (21%, 51%, 49%), and grain yield (42%, 63%, 65%) in year-1, year-2, and year-3, than respective controls. For rice crop, RHB showed the maximum increase in plant height (64%, 92%, 96%), spike length (55%, 95%, 90%), straw yield (34%, 53%, 55%), and grain yield (46%, 66%, 69%) each year (2019–2021), compared to their respective controls. The Cd immobilization was increased by the application of RHB while other treatments followed FM &gt; PrM &gt; PM &gt; control in each year of wheat and rice crops. For year-1, benefit-cost ratio remained maximum with the application of FM while for the 2nd and 3rd years in sequence, RHB proved more economical than other treatments and consistently produced wheat and rice with lower Cd concentration than FM, PrM, and PM in grains. This long-term experiment suggested that the application of organic amendments consistently increased biomass of rice and wheat and decreased the Cd concentration in tissues. The RHB remained more effective compared with FM, PrM, and PM in terms of yield, low Cd accumulation and economics of rice and wheat crops. [Display omitted] •Organic amendments enhanced wheat and rice yield under Cd stress.•Amendments differentially affected Cd availability in soil and plant uptake.•Farm manure was more effective in reducing Cd uptake by crops in 1st year.•RHB was more effective in reducing Cd uptake by crops in 2nd and 3rd year.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>38237853</pmid><doi>10.1016/j.envpol.2024.123365</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0003-3325-8254</orcidid><orcidid>https://orcid.org/0000-0002-3513-2041</orcidid><orcidid>https://orcid.org/0000-0002-9513-1729</orcidid><orcidid>https://orcid.org/0000-0001-8804-3790</orcidid><orcidid>https://orcid.org/0000-0003-0945-9224</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0269-7491
ispartof Environmental pollution (1987), 2024-03, Vol.344, p.123365-123365, Article 123365
issn 0269-7491
1873-6424
1873-6424
language eng
recordid cdi_swepub_primary_oai_slubar_slu_se_127949
source Elsevier ScienceDirect Journals; SWEPUB Freely available online
subjects Agricultural Science
Benefit-cost ratio
Cadmium
Environmental Sciences related to Agriculture and Land-use
Farm manure
Grain yield
Immobilization
Jordbruksvetenskap
Miljö- och naturvårdsvetenskap
Rice husk biochar
title Effects of agro based organic amendments on growth and cadmium uptake in wheat and rice crops irrigated with raw city effluents: Three years field study
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T03%3A43%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_swepu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20agro%20based%20organic%20amendments%20on%20growth%20and%20cadmium%20uptake%20in%20wheat%20and%20rice%20crops%20irrigated%20with%20raw%20city%20effluents:%20Three%20years%20field%20study&rft.jtitle=Environmental%20pollution%20(1987)&rft.au=Shaghaleh,%20Hiba&rft.aucorp=Sveriges%20lantbruksuniversitet&rft.date=2024-03-01&rft.volume=344&rft.spage=123365&rft.epage=123365&rft.pages=123365-123365&rft.artnum=123365&rft.issn=0269-7491&rft.eissn=1873-6424&rft_id=info:doi/10.1016/j.envpol.2024.123365&rft_dat=%3Cproquest_swepu%3E2918509753%3C/proquest_swepu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2918509753&rft_id=info:pmid/38237853&rft_els_id=S0269749124000794&rfr_iscdi=true