Oxytocin's anti-inflammatory and proimmune functions in COVID-19: a transcriptomic signature-based approach

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide pandemic, infecting over 16 million people worldwide with a significant mortality rate. However, there is no current Food and Drug Administration-approved drug that treats coronavirus disease 2019 (COVID-19). Dam...

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Veröffentlicht in:	Physiological genomics 2020-09, Vol.52 (9), p.401-407
Hauptverfasser:	Imami, Ali S, O'Donovan, Sinead M, Creeden, Justin F, Wu, Xiaojun, Eby, Hunter, McCullumsmith, Cheryl B, Uvnäs-Moberg, Kerstin, McCullumsmith, Robert E, Andari, Elissar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive Immunity - drug effects Adaptive Immunity - genetics Anti-Inflammatory Agents - pharmacology Betacoronavirus - drug effects Betacoronavirus - immunology CD40 antigen Cell activation Cell Line Coronaviridae Coronavirus Infections - drug therapy Coronavirus Infections - genetics Coronavirus Infections - immunology Coronavirus Infections - virology Coronaviruses COVID-19 Cytokine storm Databases, Genetic Gene Expression Profiling Host-Pathogen Interactions Humans Hydroxychloroquine IL-1β Immunologi inom det medicinska området Immunology in the medical area Inflammation Interleukin 6 Intravenous administration Lopinavir Lymphocytes Lymphocytes T Macrophages Oxytocin Oxytocin - analogs & derivatives Oxytocin - pharmacology Pandemics Pneumonia, Viral - drug therapy Pneumonia, Viral - genetics Pneumonia, Viral - immunology Pneumonia, Viral - virology SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 T-Lymphocytes - drug effects T-Lymphocytes - immunology T-Lymphocytes - virology Transcriptome
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