A Randomized Trial of Endometrial Scratching before In Vitro Fertilization

A Randomized Trial of Endometrial Scratching before In Vitro Fertilization

Endometrial scratching (with the use of a pipelle biopsy) is a technique proposed to facilitate embryo implantation in women undergoing in vitro fertilization. In this multicenter, open-label, randomized, controlled trial, endometrial scratching did not result in a higher rate of live birth than no...

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Veröffentlicht in:The New England journal of medicine 2019-01, Vol.380 (4), p.325-334
Hauptverfasser: Lensen, Sarah, Osavlyuk, Diana, Armstrong, Sarah, Stadelmann, Caroline, Hennes, Aurélie, Napier, Emma, Wilkinson, Jack, Sadler, Lynn, Gupta, Devashana, Strandell, Annika, Bergh, Christina, Vigneswaran, Kugajeevan, Teh, Wan T, Hamoda, Haitham, Webber, Lisa, Wakeman, Sarah A, Searle, Leigh, Bhide, Priya, McDowell, Simon, Peeraer, Karen, Khalaf, Yacoub, Farquhar, Cynthia
Format: Artikel
Sprache:eng
Schlagworte:
Bias
Biopsy
Clinical trials
Ectopic pregnancy
Embryo transfer
Embryos
Endometrium
Evidence-based medicine
Fertility
Implantation
implantation failure
In vitro fertilization
infertility
inflammation
injury
live-birth-rates
metaanalyses
Miscarriage
Obstetrics, Gynecology and Reproductive Medicine
outcomes
Pain
Pregnancy
pregnancy rate
Reproduktionsmedicin och gynekologi
women
Womens health
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Beschreibung
Zusammenfassung:Endometrial scratching (with the use of a pipelle biopsy) is a technique proposed to facilitate embryo implantation in women undergoing in vitro fertilization. In this multicenter, open-label, randomized, controlled trial, endometrial scratching did not result in a higher rate of live birth than no intervention among women undergoing IVF.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa1808737