Synthesis, DFT calculations and characterisation of new mixed Pt(II) complexes with 3-thiolanespiro-5′-hydantoin and 4-thio-1H-tetrahydropyranspiro-5′-hydantoin

Cisplatin is an anticancer drug widely used in the treatment of a wide range of solid tumours (head and neck, lung, bladder etc.), testicular and ovarian cancers. Because of its severe toxicity profile and spontaneous development of drug resistance in tumours, a number of Pt(II) complexes have been...

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Veröffentlicht in:	Chemical papers 2016, Vol.70 (1), p.93-100
Hauptverfasser:	Bakalova, Adriana, Nikolova-Mladenova, Boryana, Buyukliev, Rossen, Cherneva, Emiliya, Momekov, Georgi, Ivanov, Darvin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biotechnology Chemistry Chemistry and Materials Science Chemistry/Food Science Industrial Chemistry/Chemical Engineering Materials Science Medicinal Chemistry Original Paper
Online-Zugang:	Volltext
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