Genetic polymorphism of NAD(P)H:quinone oxidoreductase is associated with an increased risk of infant acute lymphoblastic leukemia without MLL gene rearrangements: Infant ALL

NAD(P)H:quinone oxidoreductase 1 (NQO1) is a detoxification enzyme that protects cells against oxidative stress and toxic quinones. A polymorphism (C609T) in the gene produces in the heterozygous individuals (C/T) a reduction and in those homozygous for the variant allele (T/T) the abolishment of NQ...

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Veröffentlicht in:	Leukemia 2005-02, Vol.19 (2), p.214-216
Hauptverfasser:	Lanciotti, M, Dufour, C, Corral, L, Di Michele, P, Pigullo, S, De Rossi, G, Basso, G, Leszl, A, Luciani, M, Lo Nigro, L, Micalizzi, C, Valsecchi, M G, Biondi, A, Haupt, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Research Critical Care Medicine Hematology Intensive Internal Medicine Medicine Medicine & Public Health Oncology original-manuscript
Online-Zugang:	Volltext
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