Asbestos induces selective release of lysosomal enzymes from mononuclear phagocytes
THE association of asbestos inhalation and lung disease has been recognised for many years 1 . Asbestosis is a chronic inflammatory reaction in the terminal bronchioles and alveoli of the lung with considerable fibrosis leading to distortion and eventual obliteration of the alveoli. There is also an...
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| Veröffentlicht in: | Nature (London) 1974-10, Vol.251 (5474), p.423-425 |
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| container_issue | 5474 |
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| container_title | Nature (London) |
| container_volume | 251 |
| creator | DAVIES, PHILIP ALLISON, ANTHONY C. ACKERMAN, JILL BUTTERFIELD, ANN WILLIAMS, SUSAN |
| description | THE association of asbestos inhalation and lung disease has been recognised for many years
1
. Asbestosis is a chronic inflammatory reaction in the terminal bronchioles and alveoli of the lung with considerable fibrosis leading to distortion and eventual obliteration of the alveoli. There is also an association between asbestosis and the development of bronchogenic cancer
2
and Wagner
et al.
3
have noted the occurrence of diffuse pleural and peritoneal mesotheliomas in individuals occupationally exposed to asbestos dust and in experimental animals following intrapleural injection of asbestos. |
| doi_str_mv | 10.1038/251423a0 |
| format | Article |
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1
. Asbestosis is a chronic inflammatory reaction in the terminal bronchioles and alveoli of the lung with considerable fibrosis leading to distortion and eventual obliteration of the alveoli. There is also an association between asbestosis and the development of bronchogenic cancer
2
and Wagner
et al.
3
have noted the occurrence of diffuse pleural and peritoneal mesotheliomas in individuals occupationally exposed to asbestos dust and in experimental animals following intrapleural injection of asbestos.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/251423a0</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Humanities and Social Sciences ; letter ; multidisciplinary ; Science ; Science (multidisciplinary)</subject><ispartof>Nature (London), 1974-10, Vol.251 (5474), p.423-425</ispartof><rights>Springer Nature Limited 1974</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>DAVIES, PHILIP</creatorcontrib><creatorcontrib>ALLISON, ANTHONY C.</creatorcontrib><creatorcontrib>ACKERMAN, JILL</creatorcontrib><creatorcontrib>BUTTERFIELD, ANN</creatorcontrib><creatorcontrib>WILLIAMS, SUSAN</creatorcontrib><title>Asbestos induces selective release of lysosomal enzymes from mononuclear phagocytes</title><title>Nature (London)</title><addtitle>Nature</addtitle><description>THE association of asbestos inhalation and lung disease has been recognised for many years
1
. Asbestosis is a chronic inflammatory reaction in the terminal bronchioles and alveoli of the lung with considerable fibrosis leading to distortion and eventual obliteration of the alveoli. There is also an association between asbestosis and the development of bronchogenic cancer
2
and Wagner
et al.
3
have noted the occurrence of diffuse pleural and peritoneal mesotheliomas in individuals occupationally exposed to asbestos dust and in experimental animals following intrapleural injection of asbestos.</description><subject>Humanities and Social Sciences</subject><subject>letter</subject><subject>multidisciplinary</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1974</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNo1kE1LxDAURYMoWEfBn5Cti-pL0jTtchj8ggEX6rok6cvYoW2GvI5Qf70VdXXP4nIvHMauBdwKUNWd1KKQysIJy0RhyrwoK3PKMgBZ5VCp8pxdEO0BQAtTZOx1TQ5pisS7sT16JE7Yo5-6T-RpIUvIY-D9TJHiYHuO49c8LLWQ4sCHOMbx6Jda4ocPu4t-npAu2VmwPeHVX67Y-8P92-Yp3748Pm_W25yEqKc8CIWtVCi98M4K45yqndaAxmJYyBUYilJj6aWvQ1VrpbWuTKtraaAuvVqxm99dOqRu3GFq9vGYxuWyEdD82Gj-bahv_VlTvw</recordid><startdate>19741004</startdate><enddate>19741004</enddate><creator>DAVIES, PHILIP</creator><creator>ALLISON, ANTHONY C.</creator><creator>ACKERMAN, JILL</creator><creator>BUTTERFIELD, ANN</creator><creator>WILLIAMS, SUSAN</creator><general>Nature Publishing Group UK</general><scope/></search><sort><creationdate>19741004</creationdate><title>Asbestos induces selective release of lysosomal enzymes from mononuclear phagocytes</title><author>DAVIES, PHILIP ; ALLISON, ANTHONY C. ; ACKERMAN, JILL ; BUTTERFIELD, ANN ; WILLIAMS, SUSAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-s119t-f13ed23e2c1cba17bb39b550e7aef9b5b4ef465e6c2c9f895355587d5927096c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1974</creationdate><topic>Humanities and Social Sciences</topic><topic>letter</topic><topic>multidisciplinary</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DAVIES, PHILIP</creatorcontrib><creatorcontrib>ALLISON, ANTHONY C.</creatorcontrib><creatorcontrib>ACKERMAN, JILL</creatorcontrib><creatorcontrib>BUTTERFIELD, ANN</creatorcontrib><creatorcontrib>WILLIAMS, SUSAN</creatorcontrib><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DAVIES, PHILIP</au><au>ALLISON, ANTHONY C.</au><au>ACKERMAN, JILL</au><au>BUTTERFIELD, ANN</au><au>WILLIAMS, SUSAN</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Asbestos induces selective release of lysosomal enzymes from mononuclear phagocytes</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><date>1974-10-04</date><risdate>1974</risdate><volume>251</volume><issue>5474</issue><spage>423</spage><epage>425</epage><pages>423-425</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>THE association of asbestos inhalation and lung disease has been recognised for many years
1
. Asbestosis is a chronic inflammatory reaction in the terminal bronchioles and alveoli of the lung with considerable fibrosis leading to distortion and eventual obliteration of the alveoli. There is also an association between asbestosis and the development of bronchogenic cancer
2
and Wagner
et al.
3
have noted the occurrence of diffuse pleural and peritoneal mesotheliomas in individuals occupationally exposed to asbestos dust and in experimental animals following intrapleural injection of asbestos.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><doi>10.1038/251423a0</doi><tpages>3</tpages></addata></record> |
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| ispartof | Nature (London), 1974-10, Vol.251 (5474), p.423-425 |
| issn | 0028-0836 1476-4687 |
| language | eng |
| recordid | cdi_springer_journals_10_1038_251423a0 |
| source | Nature; Alma/SFX Local Collection |
| subjects | Humanities and Social Sciences letter multidisciplinary Science Science (multidisciplinary) |
| title | Asbestos induces selective release of lysosomal enzymes from mononuclear phagocytes |
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