Symptomatic Models of Parkinson’s Disease and L-DOPA-Induced Dyskinesia in Non-human Primates

Models of Parkinson’s disease (PD) can be produced in several non-human primate (NHP) species by applying neurotoxic lesions to the nigrostriatal dopamine pathway. The most commonly used neurotoxin is MPTP, a compound accidentally discovered as a contaminant of street drugs. Compared to other neurot...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease 2015-01, Vol.22, p.221-235
Hauptverfasser:	Johnston, Tom M., Fox, Susan H.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - pharmacology 6-hydroxydopamine Animals Disease Models, Animal Dopamine Agents - pharmacology Dyskinesia Dyskinesia, Drug-Induced Humans Levodopa - pharmacology MPTP Non-human primate Non-motor Parkinson Disease - therapy Primates
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!