MitoPho8Δ60 Assay as a Tool to Quantitatively Measure Mitophagy Activity

Mitophagy, a selective type of macroautophagy (hereafter referred to as autophagy), specifically mediates the vacuole/lysosome-dependent degradation of damaged or surplus mitochondria. Because this process regulates the number and quality of mitochondria, it is vital for proper cellular homeostasis....

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Veröffentlicht in:	Methods in molecular biology (Clifton, N.J.) N.J.), 2018, Vol.1759, p.85-93
Hauptverfasser:	Yao, Zhiyuan, Liu, Xu, Klionsky, Daniel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - genetics Alkaline Phosphatase - metabolism Autophagy Biological Assay Humans Mitochondria Mitochondria - genetics Mitochondria - metabolism Mitophagy Models, Biological Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Stress Stress, Physiological Vacuole Vacuoles - metabolism Yeast
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