Farnesyl Protein Transferase Inhibitors: Medicinal Chemistry, Molecular Mechanisms, and Progress in the Clinic

Over a decade has passed since the first report describing farnesyl protein transferase (FTase)and tetrapeptide inhibitors triggered a search for small-molecule inhibitors that could be developedas oral therapeutics. There are now several farnesyl protein inhibitors (FTIs) in various phases of clini...

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Bibliographische Detailangaben

Hauptverfasser:	End, D. W., Mevellec, L., Angibaud, P.
Format:	Buchkapitel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Farnesyl transferase inhibitor Protein prenylation Ras protein
Online-Zugang:	Volltext
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