Development of a new illumination procedure for photodynamic therapy of the abdominal cavity

A homogeneous illumination of intra-abdominal organs is essential for successful photodynamic therapy of the abdominal cavity. Considering the current lack of outstanding light-delivery systems, a new illumination procedure was assessed. A rat model of peritoneal carcinomatosis was used. Four hours...

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Veröffentlicht in:	Journal of Biomedical Optics 2012-03, Vol.17 (3), p.038001-038008
Hauptverfasser:	Guyon, Laurie, Claude Lesage, Jean, Betrouni, Nacim, Mordon, Serge
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Cavity - anatomy & histology Abdominal Cavity - pathology Adenocarcinoma - drug therapy Adenocarcinoma - pathology Aminolevulinic Acid - analogs & derivatives Aminolevulinic Acid - pharmacology Animals Cell Line, Tumor Female Fluorescence hexaminolevulinate Holes Illumination Intestines - chemistry Intestines - radiation effects Lesions light dosimetry Liver Liver - chemistry Liver - radiation effects Magnetic Resonance Imaging - methods Mathematical models Ovarian Neoplasms - drug therapy Ovarian Neoplasms - pathology peritoneal carcinomatosis Peritoneal Neoplasms - drug therapy Peritoneal Neoplasms - pathology photobleaching Photochemotherapy - instrumentation Photochemotherapy - methods photodynamic therapy Photosensitizing Agents - pharmacology Position (location) Radiometry - instrumentation Radiometry - methods Rats Rats, Inbred F344 Spectrometry, Fluorescence - methods Statistics, Nonparametric Tumors
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