WE-H-BRA-03: Development of a Model to Include the Evolution of Resistant Tumor Subpopulations Into the Treatment Optimization Process for Schedules Involving Targeted Agents in Chemoradiation Therapy

Purpose: To develop a model that includes the process of resistance development into the treatment optimization process for schedules that include targeted therapies. Further, to validate the approach using clinical data and to apply the model to assess the optimal induction period with targeted age...

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Veröffentlicht in:	Medical physics (Lancaster) 2016-06, Vol.43 (6), p.3843-3843
Hauptverfasser:	Grassberger, C, Paganetti, H
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Agent based models Biomedical modeling BIOMEDICAL RADIOGRAPHY Cancer CHEMOTHERAPY CLINICAL TRIALS Computer modeling Lungs Medical treatment optimization NEOPLASMS Nonlinear dynamics OPTIMIZATION PATIENTS RADIATION PROTECTION AND DOSIMETRY Radiation treatment SCHEDULES STOCHASTIC PROCESSES
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