SU‐GG‐I‐150: Osteolytic Metastases Quantification From Digitized Radiographs
Purpose: To assess a gray level parameter in order to characterize osteolytic metastases and to compare with healthy bone on digitized radiographs. Method and Materials: The authors previously developed a computerized method in order to characterize healthy bone on digitized radiographs. We obtained...
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| Veröffentlicht in: | Medical Physics 2008-06, Vol.35 (6), p.2676-2676 |
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| creator | Sánchez, A Baltasar González‐Sistal, A |
| description | Purpose: To assess a gray level parameter in order to characterize osteolytic metastases and to compare with healthy bone on digitized radiographs. Method and Materials: The authors previously developed a computerized method in order to characterize healthy bone on digitized radiographs. We obtained an optimized healthy bone classification to compare with pathological bone: cortical, trabecular and flat bone. In the present study, 144 healthy bone and 45 osteolytic metastases radiographs corresponding to 189 different patients of both sexes were digitized (size of 0.175‐mm pixel and 4,096 gray levels). Osteolytic metastases were classified in non flat bone (OL1, n = 15) and flat bone (OL2, n = 30). The radiological images were processed using a lowpass filter and analyzed calculating gray level histograms on digitized radiographs. The parameter calculated was: mean gray level (MGL: 0 – 4096). Results: The results indicate that there are significant differences in mean values (p |
| doi_str_mv | 10.1118/1.2961548 |
| format | Article |
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Acknowledgments: Supported in part by “Fundació Universitària Agustí Pedro i Pons”</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1118/1.2961548</identifier><identifier>CODEN: MPHYA6</identifier><language>eng</language><publisher>American Association of Physicists in Medicine</publisher><subject>Image analysis ; Medical imaging ; Radiography</subject><ispartof>Medical Physics, 2008-06, Vol.35 (6), p.2676-2676</ispartof><rights>American Association of Physicists in Medicine</rights><rights>2008 American Association of Physicists in Medicine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2178-1bc98846b3cf9684f1c67a9392b92e8c2cce0d3274d0df7dab1d5ee350f2b48c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1118%2F1.2961548$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>309,310,314,777,781,786,787,1412,23911,23912,25121,27905,27906,45556</link.rule.ids></links><search><creatorcontrib>Sánchez, A Baltasar</creatorcontrib><creatorcontrib>González‐Sistal, A</creatorcontrib><title>SU‐GG‐I‐150: Osteolytic Metastases Quantification From Digitized Radiographs</title><title>Medical Physics</title><description>Purpose: To assess a gray level parameter in order to characterize osteolytic metastases and to compare with healthy bone on digitized radiographs. Method and Materials: The authors previously developed a computerized method in order to characterize healthy bone on digitized radiographs. We obtained an optimized healthy bone classification to compare with pathological bone: cortical, trabecular and flat bone. In the present study, 144 healthy bone and 45 osteolytic metastases radiographs corresponding to 189 different patients of both sexes were digitized (size of 0.175‐mm pixel and 4,096 gray levels). Osteolytic metastases were classified in non flat bone (OL1, n = 15) and flat bone (OL2, n = 30). The radiological images were processed using a lowpass filter and analyzed calculating gray level histograms on digitized radiographs. The parameter calculated was: mean gray level (MGL: 0 – 4096). Results: The results indicate that there are significant differences in mean values (p<0.001) between healthy bone and osteolytic metastases. The MGL values of osteolytic metastases are: OL1 = 1630 ± 255 and OL2 = 1742 ± 278, and the healthy bone groups: Flat: 3360 ± 301, Cortical: 3440 ± 239 and Trabecular: 2752 ± 223. The values of healthy bone were greater than osteolytic metasases. Conclusion: Our results show that the use of MGL quantify healthy bone and osteolytic zones accurately. Assessment of MGL on digitized skeletal radiographs is a reliable method for radiological exploration.
Acknowledgments: Supported in part by “Fundació Universitària Agustí Pedro i Pons”</description><subject>Image analysis</subject><subject>Medical imaging</subject><subject>Radiography</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNp9kM1OwkAUhSdGExFd-AbdalK8dzptZ9wZFCSBoCjrZjo_OAYo6QwxdeUj-Iw-iVXYanJ_Nl9OzjmEnCP0EJFfYY-KDFPGD0iHsjyJGQVxSDoAgsWUQXpMTrx_BYAsSaFDZk_zr4_P4bA9o3Yxheto6oOplk1wKpqYIH07xkePW7kOzjolg6vW0aCuVtGtW7jg3o2OZlK7alHLzYs_JUdWLr052_8umQ_unvv38Xg6HPVvxrGimPMYSyU4Z1mZKCsyziyqLJciEbQU1HBFlTKgE5ozDdrmWpaoU2Na15aWjKukSy52uqquvK-NLTa1W8m6KRCKnzIKLPZltGy8Y9_c0jR_g8XkYc9f7nivXPgN_I_4N6Mtbwk</recordid><startdate>200806</startdate><enddate>200806</enddate><creator>Sánchez, A Baltasar</creator><creator>González‐Sistal, A</creator><general>American Association of Physicists in Medicine</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>200806</creationdate><title>SU‐GG‐I‐150: Osteolytic Metastases Quantification From Digitized Radiographs</title><author>Sánchez, A Baltasar ; González‐Sistal, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2178-1bc98846b3cf9684f1c67a9392b92e8c2cce0d3274d0df7dab1d5ee350f2b48c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Image analysis</topic><topic>Medical imaging</topic><topic>Radiography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sánchez, A Baltasar</creatorcontrib><creatorcontrib>González‐Sistal, A</creatorcontrib><collection>CrossRef</collection><jtitle>Medical Physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sánchez, A Baltasar</au><au>González‐Sistal, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>SU‐GG‐I‐150: Osteolytic Metastases Quantification From Digitized Radiographs</atitle><jtitle>Medical Physics</jtitle><date>2008-06</date><risdate>2008</risdate><volume>35</volume><issue>6</issue><spage>2676</spage><epage>2676</epage><pages>2676-2676</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><coden>MPHYA6</coden><abstract>Purpose: To assess a gray level parameter in order to characterize osteolytic metastases and to compare with healthy bone on digitized radiographs. Method and Materials: The authors previously developed a computerized method in order to characterize healthy bone on digitized radiographs. We obtained an optimized healthy bone classification to compare with pathological bone: cortical, trabecular and flat bone. In the present study, 144 healthy bone and 45 osteolytic metastases radiographs corresponding to 189 different patients of both sexes were digitized (size of 0.175‐mm pixel and 4,096 gray levels). Osteolytic metastases were classified in non flat bone (OL1, n = 15) and flat bone (OL2, n = 30). The radiological images were processed using a lowpass filter and analyzed calculating gray level histograms on digitized radiographs. The parameter calculated was: mean gray level (MGL: 0 – 4096). Results: The results indicate that there are significant differences in mean values (p<0.001) between healthy bone and osteolytic metastases. The MGL values of osteolytic metastases are: OL1 = 1630 ± 255 and OL2 = 1742 ± 278, and the healthy bone groups: Flat: 3360 ± 301, Cortical: 3440 ± 239 and Trabecular: 2752 ± 223. The values of healthy bone were greater than osteolytic metasases. Conclusion: Our results show that the use of MGL quantify healthy bone and osteolytic zones accurately. Assessment of MGL on digitized skeletal radiographs is a reliable method for radiological exploration.
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| source | Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
| subjects | Image analysis Medical imaging Radiography |
| title | SU‐GG‐I‐150: Osteolytic Metastases Quantification From Digitized Radiographs |
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