On the possible chemical similarity of some common antiepileptic drugs
Epilepsy is a disease that affects approximately 50 million people in developing countries. Though the exact mechanism has not been yet discovered, it should be said that some light has been shed on its cellular and network mechanisms. As a cause of this there are several drugs that manage to stop s...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Tagungsbericht |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 1 |
| container_start_page | |
| container_title | |
| container_volume | 2872 |
| creator | Xenides, Demetrios Karamanis, Panaghiotis |
| description | Epilepsy is a disease that affects approximately 50 million people in developing countries. Though the exact mechanism has not been yet discovered, it should be said that some light has been shed on its cellular and network mechanisms. As a cause of this there are several drugs that manage to stop seizures happening, however they do not cure epilepsy. Furthermore, most of these drugs are known to cause serious side effects (i.e. birth defects when the therapy occurs during pregnancy). In the present study we are aiming on a classification of 31 of the available drugs by studying their chemical similarity. For this reason we apply a rigorous approach based on tools from mathematical analysis: in particular the metric space approach. |
| doi_str_mv | 10.1063/5.0162920 |
| format | Conference Proceeding |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_scitation_primary_10_1063_5_0162920</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2869757579</sourcerecordid><originalsourceid>FETCH-LOGICAL-h2020-fa3192452911717a9a2517d28aa64ea448e15df56d536665c59b1003525af1ce3</originalsourceid><addsrcrecordid>eNo9kFFLwzAUhYMoOKcP_oOATwqduUmTNo9jOCcM9qLgW7hrU5vRNrXJhP37dWzIebhwzsfhcgh5BDYDpsSrnDFQXHN2RSYgJSSZAnVNJozpNOGp-L4ldyHsGOM6y_IJWW46GmtLex-C2zaWFrVtXYENDa51DQ4uHqivaPDtmPm29R3FLjrbu8b20RW0HPY_4Z7cVNgE-3C5U_K1fPtcrJL15v1jMV8nNWecJRUK0DyVXANkkKFGLiEreY6oUotpmluQZSVVKYVSShZSb4ExIbnECgorpuT53FtjY_rBtTgcjEdnVvO1OXks5VyByP9gZJ_ObD_4370N0ez8fujG9wzPlc7kKD1SL2cqFC5idL777wVmTpsaaS6biiM522Yu</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype><pqid>2869757579</pqid></control><display><type>conference_proceeding</type><title>On the possible chemical similarity of some common antiepileptic drugs</title><source>AIP Journals Complete</source><creator>Xenides, Demetrios ; Karamanis, Panaghiotis</creator><contributor>Vlachos, Dimitrios</contributor><creatorcontrib>Xenides, Demetrios ; Karamanis, Panaghiotis ; Vlachos, Dimitrios</creatorcontrib><description>Epilepsy is a disease that affects approximately 50 million people in developing countries. Though the exact mechanism has not been yet discovered, it should be said that some light has been shed on its cellular and network mechanisms. As a cause of this there are several drugs that manage to stop seizures happening, however they do not cure epilepsy. Furthermore, most of these drugs are known to cause serious side effects (i.e. birth defects when the therapy occurs during pregnancy). In the present study we are aiming on a classification of 31 of the available drugs by studying their chemical similarity. For this reason we apply a rigorous approach based on tools from mathematical analysis: in particular the metric space approach.</description><identifier>ISSN: 0094-243X</identifier><identifier>EISSN: 1551-7616</identifier><identifier>DOI: 10.1063/5.0162920</identifier><identifier>CODEN: APCPCS</identifier><language>eng</language><publisher>Melville: American Institute of Physics</publisher><subject>Birth defects ; Cellular communication ; Chemical fingerprinting ; Chemical Sciences ; Developing countries ; Drugs ; Epilepsy ; LDCs ; Mathematical analysis ; Metric space ; or physical chemistry ; Side effects ; Theoretical and</subject><ispartof>AIP Conference Proceedings, 2023, Vol.2872 (1)</ispartof><rights>Author(s)</rights><rights>2023 Author(s). Published by AIP Publishing.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0002-1774-7624 ; 0000-0002-6335-5824</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://pubs.aip.org/acp/article-lookup/doi/10.1063/5.0162920$$EHTML$$P50$$Gscitation$$H</linktohtml><link.rule.ids>230,309,310,314,780,784,789,790,794,885,4512,23930,23931,25140,27924,27925,76384</link.rule.ids><backlink>$$Uhttps://univ-pau.hal.science/hal-04226138$$DView record in HAL$$Hfree_for_read</backlink></links><search><contributor>Vlachos, Dimitrios</contributor><creatorcontrib>Xenides, Demetrios</creatorcontrib><creatorcontrib>Karamanis, Panaghiotis</creatorcontrib><title>On the possible chemical similarity of some common antiepileptic drugs</title><title>AIP Conference Proceedings</title><description>Epilepsy is a disease that affects approximately 50 million people in developing countries. Though the exact mechanism has not been yet discovered, it should be said that some light has been shed on its cellular and network mechanisms. As a cause of this there are several drugs that manage to stop seizures happening, however they do not cure epilepsy. Furthermore, most of these drugs are known to cause serious side effects (i.e. birth defects when the therapy occurs during pregnancy). In the present study we are aiming on a classification of 31 of the available drugs by studying their chemical similarity. For this reason we apply a rigorous approach based on tools from mathematical analysis: in particular the metric space approach.</description><subject>Birth defects</subject><subject>Cellular communication</subject><subject>Chemical fingerprinting</subject><subject>Chemical Sciences</subject><subject>Developing countries</subject><subject>Drugs</subject><subject>Epilepsy</subject><subject>LDCs</subject><subject>Mathematical analysis</subject><subject>Metric space</subject><subject>or physical chemistry</subject><subject>Side effects</subject><subject>Theoretical and</subject><issn>0094-243X</issn><issn>1551-7616</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2023</creationdate><recordtype>conference_proceeding</recordtype><recordid>eNo9kFFLwzAUhYMoOKcP_oOATwqduUmTNo9jOCcM9qLgW7hrU5vRNrXJhP37dWzIebhwzsfhcgh5BDYDpsSrnDFQXHN2RSYgJSSZAnVNJozpNOGp-L4ldyHsGOM6y_IJWW46GmtLex-C2zaWFrVtXYENDa51DQ4uHqivaPDtmPm29R3FLjrbu8b20RW0HPY_4Z7cVNgE-3C5U_K1fPtcrJL15v1jMV8nNWecJRUK0DyVXANkkKFGLiEreY6oUotpmluQZSVVKYVSShZSb4ExIbnECgorpuT53FtjY_rBtTgcjEdnVvO1OXks5VyByP9gZJ_ObD_4370N0ez8fujG9wzPlc7kKD1SL2cqFC5idL777wVmTpsaaS6biiM522Yu</recordid><startdate>20230928</startdate><enddate>20230928</enddate><creator>Xenides, Demetrios</creator><creator>Karamanis, Panaghiotis</creator><general>American Institute of Physics</general><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope><scope>1XC</scope><scope>VOOES</scope><orcidid>https://orcid.org/0000-0002-1774-7624</orcidid><orcidid>https://orcid.org/0000-0002-6335-5824</orcidid></search><sort><creationdate>20230928</creationdate><title>On the possible chemical similarity of some common antiepileptic drugs</title><author>Xenides, Demetrios ; Karamanis, Panaghiotis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h2020-fa3192452911717a9a2517d28aa64ea448e15df56d536665c59b1003525af1ce3</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Birth defects</topic><topic>Cellular communication</topic><topic>Chemical fingerprinting</topic><topic>Chemical Sciences</topic><topic>Developing countries</topic><topic>Drugs</topic><topic>Epilepsy</topic><topic>LDCs</topic><topic>Mathematical analysis</topic><topic>Metric space</topic><topic>or physical chemistry</topic><topic>Side effects</topic><topic>Theoretical and</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xenides, Demetrios</creatorcontrib><creatorcontrib>Karamanis, Panaghiotis</creatorcontrib><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xenides, Demetrios</au><au>Karamanis, Panaghiotis</au><au>Vlachos, Dimitrios</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>On the possible chemical similarity of some common antiepileptic drugs</atitle><btitle>AIP Conference Proceedings</btitle><date>2023-09-28</date><risdate>2023</risdate><volume>2872</volume><issue>1</issue><issn>0094-243X</issn><eissn>1551-7616</eissn><coden>APCPCS</coden><abstract>Epilepsy is a disease that affects approximately 50 million people in developing countries. Though the exact mechanism has not been yet discovered, it should be said that some light has been shed on its cellular and network mechanisms. As a cause of this there are several drugs that manage to stop seizures happening, however they do not cure epilepsy. Furthermore, most of these drugs are known to cause serious side effects (i.e. birth defects when the therapy occurs during pregnancy). In the present study we are aiming on a classification of 31 of the available drugs by studying their chemical similarity. For this reason we apply a rigorous approach based on tools from mathematical analysis: in particular the metric space approach.</abstract><cop>Melville</cop><pub>American Institute of Physics</pub><doi>10.1063/5.0162920</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-1774-7624</orcidid><orcidid>https://orcid.org/0000-0002-6335-5824</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0094-243X |
| ispartof | AIP Conference Proceedings, 2023, Vol.2872 (1) |
| issn | 0094-243X 1551-7616 |
| language | eng |
| recordid | cdi_scitation_primary_10_1063_5_0162920 |
| source | AIP Journals Complete |
| subjects | Birth defects Cellular communication Chemical fingerprinting Chemical Sciences Developing countries Drugs Epilepsy LDCs Mathematical analysis Metric space or physical chemistry Side effects Theoretical and |
| title | On the possible chemical similarity of some common antiepileptic drugs |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T20%3A01%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=proceeding&rft.atitle=On%20the%20possible%20chemical%20similarity%20of%20some%20common%20antiepileptic%20drugs&rft.btitle=AIP%20Conference%20Proceedings&rft.au=Xenides,%20Demetrios&rft.date=2023-09-28&rft.volume=2872&rft.issue=1&rft.issn=0094-243X&rft.eissn=1551-7616&rft.coden=APCPCS&rft_id=info:doi/10.1063/5.0162920&rft_dat=%3Cproquest_hal_p%3E2869757579%3C/proquest_hal_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2869757579&rft_id=info:pmid/&rfr_iscdi=true |