Synthesis of some new heterocyclic compounds and used in inhibiting Acinetobacter baumannii isolated from Covid-19 patients
New heterocyclic compounds (R1-R26) were synthesized, as oxazole derivatives (R7-R11) were synthesized from the cyclization of the compound (R1) with the compounds (R2-R6), then the oxazole derivatives (R7-R11) were used to synthesis the pyrimidine derivatives (R12-R16), imidazole derivatives (R17-R...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Tagungsbericht |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 1 |
| container_start_page | |
| container_title | |
| container_volume | 2834 |
| creator | Abdul-Amir, R. M. Atia, A. K. Al-Fartusie, F. S. |
| description | New heterocyclic compounds (R1-R26) were synthesized, as oxazole derivatives (R7-R11) were synthesized from the cyclization of the compound (R1) with the compounds (R2-R6), then the oxazole derivatives (R7-R11) were used to synthesis the pyrimidine derivatives (R12-R16), imidazole derivatives (R17-R21), and pyrazole derivatives (R22-R26) from the reaction it’s with different compounds, all compounds were characterized using infrared spectra, nuclear magnetic resonance, mass, and physical properties. Then the effectiveness of these compounds was tested on the inhibition of Acinetobacter baumannii isolated from swabs and urine of COVID-19 patients in Respiratory Care units in Iraq and the results showed that the compounds (R1-R26) with three concentrations (1000, 500, 250ppm), respectively, had an inhibitory effect on the isolated bacteria compared to the antibiotics used in the hospital, which did not show any effectiveness in inhibiting this type of bacteria. |
| doi_str_mv | 10.1063/5.0161600 |
| format | Conference Proceeding |
| fullrecord | <record><control><sourceid>proquest_scita</sourceid><recordid>TN_cdi_scitation_primary_10_1063_5_0161600</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2897189957</sourcerecordid><originalsourceid>FETCH-LOGICAL-p133t-437a74f7f04e0fd31748300e1cdea399865f962fd23df12997dc4f409160f0943</originalsourceid><addsrcrecordid>eNotkFtLwzAUgIMoOKcP_oOAb0LnSZM2zeMY3mDggwq-lSwXl7EmtUmV4p83ssGBw4Hv3D6ErgksCNT0rloAqUkNcIJmpKpIwXN1imYAghUlox_n6CLGHUApOG9m6Pd18mlroos4WBxDZ7A3P3hrkhmCmtTeKaxC14fR64il13iMRmPnc2zdxiXnP_FSOW9S2EiVu_BGjp303jnsYtjLlHE7hA6vwrfTBRG4l8kZn-IlOrNyH83VMc_R-8P92-qpWL88Pq-W66InlKaCUS45s9wCM2A1JZw1FMAQpY2kQjR1ZUVdWl1SbUkpBNeKWQYia7D5bTpHN4e5_RC-RhNTuwvj4PPKtmwEJ40QFc_U7YGKyqV8YfBtP7hODlNLoP2X21btUS79A1QIbNg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype><pqid>2897189957</pqid></control><display><type>conference_proceeding</type><title>Synthesis of some new heterocyclic compounds and used in inhibiting Acinetobacter baumannii isolated from Covid-19 patients</title><source>AIP Journals Complete</source><creator>Abdul-Amir, R. M. ; Atia, A. K. ; Al-Fartusie, F. S.</creator><contributor>Obaid, Ahmed J. ; Al-Owaedi, Oday A.</contributor><creatorcontrib>Abdul-Amir, R. M. ; Atia, A. K. ; Al-Fartusie, F. S. ; Obaid, Ahmed J. ; Al-Owaedi, Oday A.</creatorcontrib><description>New heterocyclic compounds (R1-R26) were synthesized, as oxazole derivatives (R7-R11) were synthesized from the cyclization of the compound (R1) with the compounds (R2-R6), then the oxazole derivatives (R7-R11) were used to synthesis the pyrimidine derivatives (R12-R16), imidazole derivatives (R17-R21), and pyrazole derivatives (R22-R26) from the reaction it’s with different compounds, all compounds were characterized using infrared spectra, nuclear magnetic resonance, mass, and physical properties. Then the effectiveness of these compounds was tested on the inhibition of Acinetobacter baumannii isolated from swabs and urine of COVID-19 patients in Respiratory Care units in Iraq and the results showed that the compounds (R1-R26) with three concentrations (1000, 500, 250ppm), respectively, had an inhibitory effect on the isolated bacteria compared to the antibiotics used in the hospital, which did not show any effectiveness in inhibiting this type of bacteria.</description><identifier>ISSN: 0094-243X</identifier><identifier>EISSN: 1551-7616</identifier><identifier>DOI: 10.1063/5.0161600</identifier><identifier>CODEN: APCPCS</identifier><language>eng</language><publisher>Melville: American Institute of Physics</publisher><subject>Bacteria ; Effectiveness ; Heterocyclic compounds ; Imidazole ; Infrared spectra ; Magnetic properties ; NMR ; Nuclear magnetic resonance ; Oxazole ; Physical properties ; Pyrazole ; Synthesis</subject><ispartof>AIP conference proceedings, 2023, Vol.2834 (1)</ispartof><rights>Author(s)</rights><rights>2023 Author(s). Published by AIP Publishing.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://pubs.aip.org/acp/article-lookup/doi/10.1063/5.0161600$$EHTML$$P50$$Gscitation$$H</linktohtml><link.rule.ids>309,310,314,780,784,789,790,794,4512,23930,23931,25140,27924,27925,76384</link.rule.ids></links><search><contributor>Obaid, Ahmed J.</contributor><contributor>Al-Owaedi, Oday A.</contributor><creatorcontrib>Abdul-Amir, R. M.</creatorcontrib><creatorcontrib>Atia, A. K.</creatorcontrib><creatorcontrib>Al-Fartusie, F. S.</creatorcontrib><title>Synthesis of some new heterocyclic compounds and used in inhibiting Acinetobacter baumannii isolated from Covid-19 patients</title><title>AIP conference proceedings</title><description>New heterocyclic compounds (R1-R26) were synthesized, as oxazole derivatives (R7-R11) were synthesized from the cyclization of the compound (R1) with the compounds (R2-R6), then the oxazole derivatives (R7-R11) were used to synthesis the pyrimidine derivatives (R12-R16), imidazole derivatives (R17-R21), and pyrazole derivatives (R22-R26) from the reaction it’s with different compounds, all compounds were characterized using infrared spectra, nuclear magnetic resonance, mass, and physical properties. Then the effectiveness of these compounds was tested on the inhibition of Acinetobacter baumannii isolated from swabs and urine of COVID-19 patients in Respiratory Care units in Iraq and the results showed that the compounds (R1-R26) with three concentrations (1000, 500, 250ppm), respectively, had an inhibitory effect on the isolated bacteria compared to the antibiotics used in the hospital, which did not show any effectiveness in inhibiting this type of bacteria.</description><subject>Bacteria</subject><subject>Effectiveness</subject><subject>Heterocyclic compounds</subject><subject>Imidazole</subject><subject>Infrared spectra</subject><subject>Magnetic properties</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Oxazole</subject><subject>Physical properties</subject><subject>Pyrazole</subject><subject>Synthesis</subject><issn>0094-243X</issn><issn>1551-7616</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2023</creationdate><recordtype>conference_proceeding</recordtype><recordid>eNotkFtLwzAUgIMoOKcP_oOAb0LnSZM2zeMY3mDggwq-lSwXl7EmtUmV4p83ssGBw4Hv3D6ErgksCNT0rloAqUkNcIJmpKpIwXN1imYAghUlox_n6CLGHUApOG9m6Pd18mlroos4WBxDZ7A3P3hrkhmCmtTeKaxC14fR64il13iMRmPnc2zdxiXnP_FSOW9S2EiVu_BGjp303jnsYtjLlHE7hA6vwrfTBRG4l8kZn-IlOrNyH83VMc_R-8P92-qpWL88Pq-W66InlKaCUS45s9wCM2A1JZw1FMAQpY2kQjR1ZUVdWl1SbUkpBNeKWQYia7D5bTpHN4e5_RC-RhNTuwvj4PPKtmwEJ40QFc_U7YGKyqV8YfBtP7hODlNLoP2X21btUS79A1QIbNg</recordid><startdate>20231204</startdate><enddate>20231204</enddate><creator>Abdul-Amir, R. M.</creator><creator>Atia, A. K.</creator><creator>Al-Fartusie, F. S.</creator><general>American Institute of Physics</general><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>20231204</creationdate><title>Synthesis of some new heterocyclic compounds and used in inhibiting Acinetobacter baumannii isolated from Covid-19 patients</title><author>Abdul-Amir, R. M. ; Atia, A. K. ; Al-Fartusie, F. S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p133t-437a74f7f04e0fd31748300e1cdea399865f962fd23df12997dc4f409160f0943</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Bacteria</topic><topic>Effectiveness</topic><topic>Heterocyclic compounds</topic><topic>Imidazole</topic><topic>Infrared spectra</topic><topic>Magnetic properties</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Oxazole</topic><topic>Physical properties</topic><topic>Pyrazole</topic><topic>Synthesis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abdul-Amir, R. M.</creatorcontrib><creatorcontrib>Atia, A. K.</creatorcontrib><creatorcontrib>Al-Fartusie, F. S.</creatorcontrib><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abdul-Amir, R. M.</au><au>Atia, A. K.</au><au>Al-Fartusie, F. S.</au><au>Obaid, Ahmed J.</au><au>Al-Owaedi, Oday A.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Synthesis of some new heterocyclic compounds and used in inhibiting Acinetobacter baumannii isolated from Covid-19 patients</atitle><btitle>AIP conference proceedings</btitle><date>2023-12-04</date><risdate>2023</risdate><volume>2834</volume><issue>1</issue><issn>0094-243X</issn><eissn>1551-7616</eissn><coden>APCPCS</coden><abstract>New heterocyclic compounds (R1-R26) were synthesized, as oxazole derivatives (R7-R11) were synthesized from the cyclization of the compound (R1) with the compounds (R2-R6), then the oxazole derivatives (R7-R11) were used to synthesis the pyrimidine derivatives (R12-R16), imidazole derivatives (R17-R21), and pyrazole derivatives (R22-R26) from the reaction it’s with different compounds, all compounds were characterized using infrared spectra, nuclear magnetic resonance, mass, and physical properties. Then the effectiveness of these compounds was tested on the inhibition of Acinetobacter baumannii isolated from swabs and urine of COVID-19 patients in Respiratory Care units in Iraq and the results showed that the compounds (R1-R26) with three concentrations (1000, 500, 250ppm), respectively, had an inhibitory effect on the isolated bacteria compared to the antibiotics used in the hospital, which did not show any effectiveness in inhibiting this type of bacteria.</abstract><cop>Melville</cop><pub>American Institute of Physics</pub><doi>10.1063/5.0161600</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0094-243X |
| ispartof | AIP conference proceedings, 2023, Vol.2834 (1) |
| issn | 0094-243X 1551-7616 |
| language | eng |
| recordid | cdi_scitation_primary_10_1063_5_0161600 |
| source | AIP Journals Complete |
| subjects | Bacteria Effectiveness Heterocyclic compounds Imidazole Infrared spectra Magnetic properties NMR Nuclear magnetic resonance Oxazole Physical properties Pyrazole Synthesis |
| title | Synthesis of some new heterocyclic compounds and used in inhibiting Acinetobacter baumannii isolated from Covid-19 patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T08%3A02%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_scita&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=proceeding&rft.atitle=Synthesis%20of%20some%20new%20heterocyclic%20compounds%20and%20used%20in%20inhibiting%20Acinetobacter%20baumannii%20isolated%20from%20Covid-19%20patients&rft.btitle=AIP%20conference%20proceedings&rft.au=Abdul-Amir,%20R.%20M.&rft.date=2023-12-04&rft.volume=2834&rft.issue=1&rft.issn=0094-243X&rft.eissn=1551-7616&rft.coden=APCPCS&rft_id=info:doi/10.1063/5.0161600&rft_dat=%3Cproquest_scita%3E2897189957%3C/proquest_scita%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2897189957&rft_id=info:pmid/&rfr_iscdi=true |