When plasma jet-treated virgin coconut oil (VCO), is it accelerate for acute wound healing?

Background: Virgin coconut oil (VCO) has activity in accelerating wound healing by shortening complete epithelialization. Plasma Jet has the potential to accelerate wound healing. Purposes: This research was to determine the activity and effectiveness of the combination of Virgin Coconut Oil (VCO) and Plasma Jet in accelerating acute wound healing. Method: Twenty experimental mouse Balb c, male, age 5 months, were classified into 5 groups, namely, Dressing group (D), Plasma Jet Group (P), Virgin Coconut Oil Group (V), Virgin Coconut Oil treated Plasma Jet Group (VP), and Plasma Jet-treated Virgin Coconut Oil Group (PV). The research was conducted to determine the implications between Virgin Coconut Oil (VCO) and Plasma Jet for acute wound healing in a small animal model (mice) by mimicking a clinical setting. Virgin Coconut Oil was prepared. They were treated by atmospheric Plasma Jet with a distance of 20 mm for 3 minutes before and after their application. The analysis of wound contraction was calculated using a mathematic formula based on wound area measurement supported by computer software Scion. Discussion: The wound size percentage in groups containing Virgin Coconut Oil treated Plasma Jet Group (VP) was higher than that in all groups. This investigation was also Virgin Coconut Oil Group (V) showed that was slightly lower than that in the Dressing Group (D) and Plasma Group (P). Results: Plasma Jet treated Virgin Coconut Oil Group has the smallest size wound of the wound healing activity. Plasma Jet may better support Virgin Coconut Oil for acute wound healing.