Molecular modeling study and antifungal activity of some synthesized quinoline derivatives
The chemical reactivity and stability of three prepared compounds (5-7) have been studied using molecular modelling. According to the results, compound 7 is more reactive than compounds 5 and 6. Antifungal activity was confirmed for all the compounds and proved that the compound 6 has been shown to...
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creator | Zinad, Dhafer S. Salman, Ghazwan A. Mahal, Ahmed Hussein, Fadhela M. |
description | The chemical reactivity and stability of three prepared compounds (5-7) have been studied using molecular modelling. According to the results, compound 7 is more reactive than compounds 5 and 6. Antifungal activity was confirmed for all the compounds and proved that the compound 6 has been shown to have a potent zone of inhibition against Aspergillus niger in comparison to the reference drug used of Amphotericin B, while compounds 5 and 7 showed significant activity than the positive control. |
doi_str_mv | 10.1063/5.0118611 |
format | Conference Proceeding |
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According to the results, compound 7 is more reactive than compounds 5 and 6. Antifungal activity was confirmed for all the compounds and proved that the compound 6 has been shown to have a potent zone of inhibition against Aspergillus niger in comparison to the reference drug used of Amphotericin B, while compounds 5 and 7 showed significant activity than the positive control.</abstract><cop>Melville</cop><pub>American Institute of Physics</pub><doi>10.1063/5.0118611</doi><tpages>7</tpages></addata></record> |
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language | eng |
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source | AIP Journals Complete |
subjects | Chemical synthesis Fungicides Quinoline |
title | Molecular modeling study and antifungal activity of some synthesized quinoline derivatives |
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