An automated 3D visible light stereolithography platform for hydrogel-based micron-sized structures
The tiny volume and multifunction of micron-sized biomaterial structure make them necessary for work in vivo environment, and hydrogel-based micron-sized structure is biocompatible and have easy controllable swollen ratio and great mechanical performance. Conventional manufacturing methods still hav...
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| Veröffentlicht in: | AIP advances 2019-06, Vol.9 (6), p.065204-065204-4 |
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| container_end_page | 065204-4 |
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| creator | Li, Didi Miao, Anqi Jin, Xiansheng Shang, Xifu Liang, Haiyi Yang, Runhuai |
| description | The tiny volume and multifunction of micron-sized biomaterial structure make them necessary for work in vivo environment, and hydrogel-based micron-sized structure is biocompatible and have easy controllable swollen ratio and great mechanical performance. Conventional manufacturing methods still have limitations in producing specific structure of micron-sized structure. Besides, the precision and volume of micro structure always compromise. Here, we present a low-cost automated 3D visible light stereolithography platform for hydrogel-based high-precision micron-sized structures. The core of the platform, light engine was refitted from an ordinary commercial projector which is safe and bio-compatible. With motorized precision stage and operating system programed by open source software, the platform could build high-precision structure at micron size automatically. Three-dimensional micro structures were printed to qualify the precision and stability of the platform. This platform provides micron-sized biomaterial structure 3D printing with high precision, wide printing area, high speed and low cost for biomedical engineering applications such as cell manipulation, drug delivery and tissue engineering. |
| doi_str_mv | 10.1063/1.5097001 |
| format | Article |
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Conventional manufacturing methods still have limitations in producing specific structure of micron-sized structure. Besides, the precision and volume of micro structure always compromise. Here, we present a low-cost automated 3D visible light stereolithography platform for hydrogel-based high-precision micron-sized structures. The core of the platform, light engine was refitted from an ordinary commercial projector which is safe and bio-compatible. With motorized precision stage and operating system programed by open source software, the platform could build high-precision structure at micron size automatically. Three-dimensional micro structures were printed to qualify the precision and stability of the platform. This platform provides micron-sized biomaterial structure 3D printing with high precision, wide printing area, high speed and low cost for biomedical engineering applications such as cell manipulation, drug delivery and tissue engineering.</description><subject>Automation</subject><subject>Biocompatibility</subject><subject>Biomedical engineering</subject><subject>Biomedical materials</subject><subject>Dimensional stability</subject><subject>Drug delivery systems</subject><subject>Hydrogels</subject><subject>Lithography</subject><subject>Low cost</subject><subject>Mechanical properties</subject><subject>Production methods</subject><subject>Three dimensional printing</subject><subject>Tissue engineering</subject><issn>2158-3226</issn><issn>2158-3226</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNqdkUtLAzEQxxdRsNQe_AYLnhS25tXs5ljqq1DwoueQzWM3ZdusSbZQP73RFfXsHDIPfvOfCZNllxDMIaD4Fs4XgJUAwJNsguCiKjBC9PRPfJ7NQtiCZIRBUJFJJpf7XAzR7UTUKsd3-cEGW3c672zTxjxE7bXrbGxd40XfHvO-E9E4v8vTk7dH5V2ju6IWIbXvrPRuXwT7npIQ_SDj4HW4yM6M6IKefftp9vpw_7J6KjbPj-vVclNIgqpYIKYqrKBSCwYEQNKQCiMjDC2JhlCRWmJKFJMlLKFkhGFTl7SkBFGoJFUaT7P1qKuc2PLe253wR-6E5V8F5xsufLSy0xwoqqnEplS6IpAxJozANVKpLolSJmldjVq9d2-DDpFv3eD3aX2OEKaoZBVFiboeqfTvELw2P1Mh4J8n4ZB_nySxNyMbpI0iWrf_H3xw_hfkfdr1A7awmsY</recordid><startdate>201906</startdate><enddate>201906</enddate><creator>Li, Didi</creator><creator>Miao, Anqi</creator><creator>Jin, Xiansheng</creator><creator>Shang, Xifu</creator><creator>Liang, Haiyi</creator><creator>Yang, Runhuai</creator><general>American Institute of Physics</general><general>AIP Publishing LLC</general><scope>AJDQP</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-3529-0277</orcidid><orcidid>https://orcid.org/0000-0001-7458-8036</orcidid></search><sort><creationdate>201906</creationdate><title>An automated 3D visible light stereolithography platform for hydrogel-based micron-sized structures</title><author>Li, Didi ; Miao, Anqi ; Jin, Xiansheng ; Shang, Xifu ; Liang, Haiyi ; Yang, Runhuai</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c428t-29d83d1dd590a02cf4832faf674e11d4bc364d9c7171c9493fb76764261dc6de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Automation</topic><topic>Biocompatibility</topic><topic>Biomedical engineering</topic><topic>Biomedical materials</topic><topic>Dimensional stability</topic><topic>Drug delivery systems</topic><topic>Hydrogels</topic><topic>Lithography</topic><topic>Low cost</topic><topic>Mechanical properties</topic><topic>Production methods</topic><topic>Three dimensional printing</topic><topic>Tissue engineering</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Didi</creatorcontrib><creatorcontrib>Miao, Anqi</creatorcontrib><creatorcontrib>Jin, Xiansheng</creatorcontrib><creatorcontrib>Shang, Xifu</creatorcontrib><creatorcontrib>Liang, Haiyi</creatorcontrib><creatorcontrib>Yang, Runhuai</creatorcontrib><collection>AIP Open Access Journals</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>AIP advances</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Didi</au><au>Miao, Anqi</au><au>Jin, Xiansheng</au><au>Shang, Xifu</au><au>Liang, Haiyi</au><au>Yang, Runhuai</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An automated 3D visible light stereolithography platform for hydrogel-based micron-sized structures</atitle><jtitle>AIP advances</jtitle><date>2019-06</date><risdate>2019</risdate><volume>9</volume><issue>6</issue><spage>065204</spage><epage>065204-4</epage><pages>065204-065204-4</pages><issn>2158-3226</issn><eissn>2158-3226</eissn><coden>AAIDBI</coden><abstract>The tiny volume and multifunction of micron-sized biomaterial structure make them necessary for work in vivo environment, and hydrogel-based micron-sized structure is biocompatible and have easy controllable swollen ratio and great mechanical performance. Conventional manufacturing methods still have limitations in producing specific structure of micron-sized structure. Besides, the precision and volume of micro structure always compromise. Here, we present a low-cost automated 3D visible light stereolithography platform for hydrogel-based high-precision micron-sized structures. The core of the platform, light engine was refitted from an ordinary commercial projector which is safe and bio-compatible. With motorized precision stage and operating system programed by open source software, the platform could build high-precision structure at micron size automatically. Three-dimensional micro structures were printed to qualify the precision and stability of the platform. 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| ispartof | AIP advances, 2019-06, Vol.9 (6), p.065204-065204-4 |
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| source | DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | Automation Biocompatibility Biomedical engineering Biomedical materials Dimensional stability Drug delivery systems Hydrogels Lithography Low cost Mechanical properties Production methods Three dimensional printing Tissue engineering |
| title | An automated 3D visible light stereolithography platform for hydrogel-based micron-sized structures |
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