Preparation and characterization of CuO NPs via laser ablation under electric field and study their antibacterial activity
Antibiotic activity of copper oxide (CuO) nanoparticles (NPs) produced via pulse laser ablation in liquid (PLAL) process with the electric field was investigated. The optical and structural properties for CuO NPs were characterized using FTIR, UV-VIS, and AFM. In case of CuO only, it was found to ha...
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| creator | Fadhil, Fattin A. Hasoon, Buthenia A. Hussein, Nehia N. Khashan, Khawla S. |
| description | Antibiotic activity of copper oxide (CuO) nanoparticles (NPs) produced via pulse laser ablation in liquid (PLAL) process with the electric field was investigated. The optical and structural properties for CuO NPs were characterized using FTIR, UV-VIS, and AFM. In case of CuO only, it was found to have an effect on all bacterial species with some variation. However, when NPs are mixed with antibiotics, there is an obvious many difference in the antibacterial activity towards bacteria. This is evidence of a synergistic effect between the two NPs and antibiotics. We found that the percentage of increased inhibitory effect has increased against the Gram-negative bacteria, as in the combination of (Ampicillin and Gentamicin) with NPs (47% and 46%, respectively) against E. coli (60%, 67%, 60%, and 150%, respectively) against the intestinal bacteria. In addition, there is a significant increase in the ratio of antibacterial activity against pathogens by the combination of antibiotics (Cefotaxime, Gentamicin, and Ampicillin) with NPs on the growth of E. coli bacteria. |
| doi_str_mv | 10.1063/1.5080815 |
| format | Conference Proceeding |
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The optical and structural properties for CuO NPs were characterized using FTIR, UV-VIS, and AFM. In case of CuO only, it was found to have an effect on all bacterial species with some variation. However, when NPs are mixed with antibiotics, there is an obvious many difference in the antibacterial activity towards bacteria. This is evidence of a synergistic effect between the two NPs and antibiotics. We found that the percentage of increased inhibitory effect has increased against the Gram-negative bacteria, as in the combination of (Ampicillin and Gentamicin) with NPs (47% and 46%, respectively) against E. coli (60%, 67%, 60%, and 150%, respectively) against the intestinal bacteria. 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The optical and structural properties for CuO NPs were characterized using FTIR, UV-VIS, and AFM. In case of CuO only, it was found to have an effect on all bacterial species with some variation. However, when NPs are mixed with antibiotics, there is an obvious many difference in the antibacterial activity towards bacteria. This is evidence of a synergistic effect between the two NPs and antibiotics. We found that the percentage of increased inhibitory effect has increased against the Gram-negative bacteria, as in the combination of (Ampicillin and Gentamicin) with NPs (47% and 46%, respectively) against E. coli (60%, 67%, 60%, and 150%, respectively) against the intestinal bacteria. In addition, there is a significant increase in the ratio of antibacterial activity against pathogens by the combination of antibiotics (Cefotaxime, Gentamicin, and Ampicillin) with NPs on the growth of E. coli bacteria.</description><subject>Ampicillin</subject><subject>Antibiotics</subject><subject>Bacteria</subject><subject>Copper oxides</subject><subject>E coli</subject><subject>Electric fields</subject><subject>Laser ablation</subject><subject>Nanoparticles</subject><subject>Optical properties</subject><subject>Synergistic effect</subject><issn>0094-243X</issn><issn>1551-7616</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2018</creationdate><recordtype>conference_proceeding</recordtype><recordid>eNotUMtqwzAQFKWFpmkP_QNBbwWnWj0s-1hCXxCaHHLozWxkmSi4dirJAefr68Q57c7uMLM7hDwCmwFLxQvMFMtYBuqKTEApSHQK6TWZMJbLhEvxc0vuQtgxxnOtswk5rrzdo8fo2oZiU1KzHZCJ1rvjOGwrOu-W9HsV6MEhrTFYT3FTj9uuKQdoa2uid4ZWztblWSfEruxp3Fo3sJvoNqMo1nRo3MHF_p7cVFgH-3CpU7J-f1vPP5PF8uNr_rpIDM9FTDizZjOcD6BRpVxrRGtKAVxlQgqbK6w05ilkBlGUUktpOLC8UlILlnMxJU-j7N63f50Nsdi1nW8Gx4LDEFbKNJxYzyMrGBfPrxV7737R9wWw4hRtAcUlWvEPEMNrxw</recordid><startdate>20181206</startdate><enddate>20181206</enddate><creator>Fadhil, Fattin A.</creator><creator>Hasoon, Buthenia A.</creator><creator>Hussein, Nehia N.</creator><creator>Khashan, Khawla S.</creator><general>American Institute of Physics</general><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>20181206</creationdate><title>Preparation and characterization of CuO NPs via laser ablation under electric field and study their antibacterial activity</title><author>Fadhil, Fattin A. ; Hasoon, Buthenia A. ; Hussein, Nehia N. ; Khashan, Khawla S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c293t-20ecb009117a56277aaecd31258343e95af7a9618caa3d4744c2109f54730923</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Ampicillin</topic><topic>Antibiotics</topic><topic>Bacteria</topic><topic>Copper oxides</topic><topic>E coli</topic><topic>Electric fields</topic><topic>Laser ablation</topic><topic>Nanoparticles</topic><topic>Optical properties</topic><topic>Synergistic effect</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fadhil, Fattin A.</creatorcontrib><creatorcontrib>Hasoon, Buthenia A.</creatorcontrib><creatorcontrib>Hussein, Nehia N.</creatorcontrib><creatorcontrib>Khashan, Khawla S.</creatorcontrib><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fadhil, Fattin A.</au><au>Hasoon, Buthenia A.</au><au>Hussein, Nehia N.</au><au>Khashan, Khawla S.</au><au>Ismail, Nur Syakimah</au><au>Ramli, Muhammad Mahyiddin</au><au>Wei-Wen, Liu</au><au>Hong, Voon Chun</au><au>Isa, Siti Salwa Mat</au><au>Fathil, Mohamad Faris Mohamad</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Preparation and characterization of CuO NPs via laser ablation under electric field and study their antibacterial activity</atitle><btitle>AIP conference proceedings</btitle><date>2018-12-06</date><risdate>2018</risdate><volume>2045</volume><issue>1</issue><issn>0094-243X</issn><eissn>1551-7616</eissn><coden>APCPCS</coden><abstract>Antibiotic activity of copper oxide (CuO) nanoparticles (NPs) produced via pulse laser ablation in liquid (PLAL) process with the electric field was investigated. The optical and structural properties for CuO NPs were characterized using FTIR, UV-VIS, and AFM. In case of CuO only, it was found to have an effect on all bacterial species with some variation. However, when NPs are mixed with antibiotics, there is an obvious many difference in the antibacterial activity towards bacteria. This is evidence of a synergistic effect between the two NPs and antibiotics. We found that the percentage of increased inhibitory effect has increased against the Gram-negative bacteria, as in the combination of (Ampicillin and Gentamicin) with NPs (47% and 46%, respectively) against E. coli (60%, 67%, 60%, and 150%, respectively) against the intestinal bacteria. 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| fulltext | fulltext |
| identifier | ISSN: 0094-243X |
| ispartof | AIP conference proceedings, 2018, Vol.2045 (1) |
| issn | 0094-243X 1551-7616 |
| language | eng |
| recordid | cdi_scitation_primary_10_1063_1_5080815 |
| source | AIP Journals Complete |
| subjects | Ampicillin Antibiotics Bacteria Copper oxides E coli Electric fields Laser ablation Nanoparticles Optical properties Synergistic effect |
| title | Preparation and characterization of CuO NPs via laser ablation under electric field and study their antibacterial activity |
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