Formation of the multifunctional metal-polymer composite with antiseptic, anesthetic and bactericidal properties by green technologies
The preparation technique for multifunctional metal-polymer composites based on the commercial medical sponge Collachit-G with antiseptic, anesthetic and bactericidal properties has been developed. The immobilization of ibuprofen and silver nanoparticles on/into polymer was achieved by using combina...
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| creator | Said-Galiev, E. E. Rubina, M. S. Vasil’kov, A. Yu Naumkin, A. V. Khokhlov, A. R. Abd-Elsalam, K. A. |
| description | The preparation technique for multifunctional metal-polymer composites based on the commercial medical sponge Collachit-G with antiseptic, anesthetic and bactericidal properties has been developed. The immobilization of ibuprofen and silver nanoparticles on/into polymer was achieved by using combination of two green technologies: the treatment in supercritical carbon dioxide and metal vapor synthesis. The composites were investigated by XRFA, TEM and XPS. A drug- release process and its mechanism have been studied within the framework of the Ritger-Peppas model. It was found that ibuprofen content in the sponge reaches 51 % from its weight. The average linear size of silver particles is 6 ± 1nm, and silver atoms are in non-oxidized state. Duration of ibuprofen escape from initial sponge in the phosphate buffer with pH =7.4 is 3 hours. Diffusion obeys to Fick’s law. The presence of Ag clusters in the sponge does not principally change the diffusion mechanism. |
| doi_str_mv | 10.1063/1.5046021 |
| format | Conference Proceeding |
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E. ; Rubina, M. S. ; Vasil’kov, A. Yu ; Naumkin, A. V. ; Khokhlov, A. R. ; Abd-Elsalam, K. A.</creator><contributor>Acierno, Domenico ; D’Amore, Alberto ; Grassia, Luigi</contributor><creatorcontrib>Said-Galiev, E. E. ; Rubina, M. S. ; Vasil’kov, A. Yu ; Naumkin, A. V. ; Khokhlov, A. R. ; Abd-Elsalam, K. A. ; Acierno, Domenico ; D’Amore, Alberto ; Grassia, Luigi</creatorcontrib><description>The preparation technique for multifunctional metal-polymer composites based on the commercial medical sponge Collachit-G with antiseptic, anesthetic and bactericidal properties has been developed. The immobilization of ibuprofen and silver nanoparticles on/into polymer was achieved by using combination of two green technologies: the treatment in supercritical carbon dioxide and metal vapor synthesis. The composites were investigated by XRFA, TEM and XPS. A drug- release process and its mechanism have been studied within the framework of the Ritger-Peppas model. It was found that ibuprofen content in the sponge reaches 51 % from its weight. The average linear size of silver particles is 6 ± 1nm, and silver atoms are in non-oxidized state. Duration of ibuprofen escape from initial sponge in the phosphate buffer with pH =7.4 is 3 hours. Diffusion obeys to Fick’s law. The presence of Ag clusters in the sponge does not principally change the diffusion mechanism.</description><identifier>ISSN: 0094-243X</identifier><identifier>EISSN: 1551-7616</identifier><identifier>DOI: 10.1063/1.5046021</identifier><identifier>CODEN: APCPCS</identifier><language>eng</language><publisher>Melville: American Institute of Physics</publisher><subject>Carbon dioxide ; Ibuprofen ; Metal vapors ; Nonsteroidal anti-inflammatory drugs ; Polymer matrix composites ; Polymers ; Silver ; Weight</subject><ispartof>AIP conference proceedings, 2018, Vol.1981 (1)</ispartof><rights>Author(s)</rights><rights>2018 Author(s). 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A.</creatorcontrib><title>Formation of the multifunctional metal-polymer composite with antiseptic, anesthetic and bactericidal properties by green technologies</title><title>AIP conference proceedings</title><description>The preparation technique for multifunctional metal-polymer composites based on the commercial medical sponge Collachit-G with antiseptic, anesthetic and bactericidal properties has been developed. The immobilization of ibuprofen and silver nanoparticles on/into polymer was achieved by using combination of two green technologies: the treatment in supercritical carbon dioxide and metal vapor synthesis. The composites were investigated by XRFA, TEM and XPS. A drug- release process and its mechanism have been studied within the framework of the Ritger-Peppas model. It was found that ibuprofen content in the sponge reaches 51 % from its weight. The average linear size of silver particles is 6 ± 1nm, and silver atoms are in non-oxidized state. Duration of ibuprofen escape from initial sponge in the phosphate buffer with pH =7.4 is 3 hours. Diffusion obeys to Fick’s law. The presence of Ag clusters in the sponge does not principally change the diffusion mechanism.</description><subject>Carbon dioxide</subject><subject>Ibuprofen</subject><subject>Metal vapors</subject><subject>Nonsteroidal anti-inflammatory drugs</subject><subject>Polymer matrix composites</subject><subject>Polymers</subject><subject>Silver</subject><subject>Weight</subject><issn>0094-243X</issn><issn>1551-7616</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2018</creationdate><recordtype>conference_proceeding</recordtype><recordid>eNp9kM9KAzEYxIMoWKsH3yDgTdyaP7vZ5CjFqiB4UfAWstlsm7K7iUmq9AV8blNb8ObpGz5-DDMDwCVGM4wYvcWzCpUMEXwEJriqcFEzzI7BBCFRFqSk76fgLMY1QkTUNZ-A74ULg0rWjdB1MK0MHDZ9st1m1Lun6uFgkuoL7_rtYALUbvAu2mTgl00rqMZko_HJ6pusTcwGWWfZwkbpZILVts0mPjhvQrImwmYLl8GYESajV6Pr3TJ_z8FJp_poLg53Ct4W96_zx-L55eFpfvdceFLRVDRE5Ni5ESorXAumOGVE6K7sMKMVR0wTYgTJ9SlveceNUoI3jRZIt2XTcDoFV3vfHOhjk_PKtduEXDNKgnjNKCG0ztT1norapt9xpA92UGErMZK7nSWWh53_gz9d-AOlbzv6Az1AgOE</recordid><startdate>20180711</startdate><enddate>20180711</enddate><creator>Said-Galiev, E. E.</creator><creator>Rubina, M. S.</creator><creator>Vasil’kov, A. Yu</creator><creator>Naumkin, A. V.</creator><creator>Khokhlov, A. R.</creator><creator>Abd-Elsalam, K. A.</creator><general>American Institute of Physics</general><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>20180711</creationdate><title>Formation of the multifunctional metal-polymer composite with antiseptic, anesthetic and bactericidal properties by green technologies</title><author>Said-Galiev, E. E. ; Rubina, M. S. ; Vasil’kov, A. Yu ; Naumkin, A. V. ; Khokhlov, A. R. ; Abd-Elsalam, K. 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A.</au><au>Acierno, Domenico</au><au>D’Amore, Alberto</au><au>Grassia, Luigi</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Formation of the multifunctional metal-polymer composite with antiseptic, anesthetic and bactericidal properties by green technologies</atitle><btitle>AIP conference proceedings</btitle><date>2018-07-11</date><risdate>2018</risdate><volume>1981</volume><issue>1</issue><issn>0094-243X</issn><eissn>1551-7616</eissn><coden>APCPCS</coden><abstract>The preparation technique for multifunctional metal-polymer composites based on the commercial medical sponge Collachit-G with antiseptic, anesthetic and bactericidal properties has been developed. The immobilization of ibuprofen and silver nanoparticles on/into polymer was achieved by using combination of two green technologies: the treatment in supercritical carbon dioxide and metal vapor synthesis. The composites were investigated by XRFA, TEM and XPS. A drug- release process and its mechanism have been studied within the framework of the Ritger-Peppas model. It was found that ibuprofen content in the sponge reaches 51 % from its weight. The average linear size of silver particles is 6 ± 1nm, and silver atoms are in non-oxidized state. Duration of ibuprofen escape from initial sponge in the phosphate buffer with pH =7.4 is 3 hours. Diffusion obeys to Fick’s law. The presence of Ag clusters in the sponge does not principally change the diffusion mechanism.</abstract><cop>Melville</cop><pub>American Institute of Physics</pub><doi>10.1063/1.5046021</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0094-243X |
| ispartof | AIP conference proceedings, 2018, Vol.1981 (1) |
| issn | 0094-243X 1551-7616 |
| language | eng |
| recordid | cdi_scitation_primary_10_1063_1_5046021 |
| source | AIP Journals Complete |
| subjects | Carbon dioxide Ibuprofen Metal vapors Nonsteroidal anti-inflammatory drugs Polymer matrix composites Polymers Silver Weight |
| title | Formation of the multifunctional metal-polymer composite with antiseptic, anesthetic and bactericidal properties by green technologies |
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