Continuous sheath-free magnetic separation of particles in a U-shaped microchannel

Particle separation is important to many chemical and biomedical applications. Magnetic field-induced particle separation is simple, cheap, and free of fluid heating issues that accompany electric, acoustic, and optical methods. We develop herein a novel microfluidic approach to continuous sheath-fr...

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Veröffentlicht in:Biomicrofluidics 2012-12, Vol.6 (4), p.44106-44106
Hauptverfasser: Liang, Litao, Xuan, Xiangchun
Format: Artikel
Sprache:eng
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Zusammenfassung:Particle separation is important to many chemical and biomedical applications. Magnetic field-induced particle separation is simple, cheap, and free of fluid heating issues that accompany electric, acoustic, and optical methods. We develop herein a novel microfluidic approach to continuous sheath-free magnetic separation of particles. This approach exploits the negative or positive magnetophoretic deflection to focus and separate particles in the two branches of a U-shaped microchannel, respectively. It is applicable to both magnetic and diamagnetic particle separations, and is demonstrated through the sorting of 5 μm and 15 μm polystyrene particles suspended in a dilute ferrofluid.
ISSN:1932-1058
1932-1058
DOI:10.1063/1.4765335