Integrated identification and quantification of cyanobacterial toxins from Pacific Northwest freshwaters by Liquid Chromatography and High-resolution Mass Spectrometry
The occurrence of harmful algal blooms in nutrient-rich freshwater bodies has increased world-wide, including in the Pacific Northwest. Some cyanobacterial genera have the potential to produce secondary metabolites that are highly toxic to humans, livestock and wildlife. Reliable methods for the det...
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| Veröffentlicht in: | Journal of the Mexican Chemical Society 2018-01, Vol.62 (2), p.197-213 |
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| creator | Ahn, Soyoun Magaña, Armando Alcazar Bozarth, Connie Shepardson, Jonathan Morré, Jeffery Dreher, Theo Maier, Claudia S |
| description | The occurrence of harmful algal blooms in nutrient-rich freshwater bodies has increased world-wide, including in the Pacific Northwest. Some cyanobacterial genera have the potential to produce secondary metabolites that are highly toxic to humans, livestock and wildlife. Reliable methods for the detection of cyanobacterial toxins with high specificity and low limits of detection are in high demand. Here we test a relatively new hybrid high resolution accurate mass quadrupole time-of-flight mass spectrometry platform (TripleTOF) for the analysis of cyanobacterial toxins in freshwater samples. We developed a new method that allows the quantitative analysis of four commonly observed microcystin congeners (LR, LA, YR, and RR) and anatoxin-a in a 6-min LC run without solid-phase enrichment. Limits of detection for the microcystin congeners (LR, LA, YR, and RR) and anatoxin-a were |
| doi_str_mv | 10.29356/jmcs.v62i2.386 |
| format | Article |
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| source | Free Full-Text Journals in Chemistry |
| subjects | Chemistry, Multidisciplinary |
| title | Integrated identification and quantification of cyanobacterial toxins from Pacific Northwest freshwaters by Liquid Chromatography and High-resolution Mass Spectrometry |
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