Convenient Reductive Amination of Aldehydes by NaBH4/Cation Exchange Resin

Different secondary amines have been synthesized by reductive amination a variety of aldehydes and anilines with NaBH4/DOWEX(R)50WX8 as reducing system in THF at room temperature in high to excellent yields of products (85-93%).

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Veröffentlicht in:Journal of the Mexican Chemical Society 2014-01, Vol.58 (1), p.22-26
Hauptverfasser: Setamdideh, Davood, Sepehraddin, Farhad
Format: Artikel
Sprache:eng ; por
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Zusammenfassung:Different secondary amines have been synthesized by reductive amination a variety of aldehydes and anilines with NaBH4/DOWEX(R)50WX8 as reducing system in THF at room temperature in high to excellent yields of products (85-93%).
ISSN:1870-249X