Mortality in Patients Requiring Prolonged Mechanical Ventilation: A Retrospective Cohort Study with Propensity Score Analysis
ABSTRACT Background: An increase has been observed in the number of patients requiring spe cialized care in mechanical ventilation weaning and rehabilitation centers (MVWRCs). Methods: An observational study with propensity score analysis was conducted on a 13- year cohort of patients in a MVWRC in...
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| Veröffentlicht in: | Revista americana de medicina respiratoria 2024, Vol.24 (2), p.157-166 |
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| creator | Villalba, Darío Díaz-Ballve, Ladislao Scrigna, Mariana Collins, Jessica Matesa, Amelia Áreas, Laura Golfarini, Nicolás Gil-Rossetti, Gregorio Pini, Paula Pedace, Paula Tocalini, Pablo Pérez Calvo, Eliana Planells, Fernando |
| description | ABSTRACT Background: An increase has been observed in the number of patients requiring spe cialized care in mechanical ventilation weaning and rehabilitation centers (MVWRCs). Methods: An observational study with propensity score analysis was conducted on a 13- year cohort of patients in a MVWRC in Argentina. Predictors of mortality were analyzed. Results: Mortality assessed using the inverse probability of treatment weighting was as sociated with age [OR=1.037 (95% CI: 1.023-1.052), p |
| doi_str_mv | 10.56538/ramr.mxdb9423 |
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Methods: An observational study with propensity score analysis was conducted on a 13- year cohort of patients in a MVWRC in Argentina. Predictors of mortality were analyzed. Results: Mortality assessed using the inverse probability of treatment weighting was as sociated with age [OR=1.037 (95% CI: 1.023-1.052), p<0.001], weaning from mechanical ventilation (MV) [OR=0.398 (95% CI: 0.282-0.560), p<0.001], decannulation [OR=0.059 (95% CI: 0.038-0.091), p<0.001], history of cardiovascular disease [OR=1.684 (95% CI: 1.146-2.474), p<0.001], pneumonia in non-chronic obstructive pulmonary disease (non-COPD) [OR=2.649 (95% CI: 1.631-4.302), p<0.001], and COPD [OR=0.477 (95% CI: 0.298-0.762), p=0.002]. Multiple logistic regression analysis in the propensity score-matched sample indicated that weaning from MV [OR=0.313 (95% CI: 0.137-0.715), p=0.006] and decannulation [OR=0.057 (95% CI: 0.021-0.155), p=<0.001] remained associated with lower mortal ity, whereas age [OR=1.056 (95% CI: 1.026-1.087), p=<0.001] remained a predictor associated with higher mortality. Conclusion: Mortality in patients requiring MV in a MVWRC was independently associ ated with older age, failed weaning from MV, and non-decannulation. It is very important to identify such predictors in order to plan attainable treatment goals.]]></description><identifier>ISSN: 1852-236X</identifier><identifier>EISSN: 1852-236X</identifier><identifier>DOI: 10.56538/ramr.mxdb9423</identifier><language>por</language><publisher>Asociación Argentina de Medicina Respiratoria</publisher><subject>NEUROSCIENCES</subject><ispartof>Revista americana de medicina respiratoria, 2024, Vol.24 (2), p.157-166</ispartof><rights>This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids></links><search><creatorcontrib>Villalba, Darío</creatorcontrib><creatorcontrib>Díaz-Ballve, Ladislao</creatorcontrib><creatorcontrib>Scrigna, Mariana</creatorcontrib><creatorcontrib>Collins, Jessica</creatorcontrib><creatorcontrib>Matesa, Amelia</creatorcontrib><creatorcontrib>Áreas, Laura</creatorcontrib><creatorcontrib>Golfarini, Nicolás</creatorcontrib><creatorcontrib>Gil-Rossetti, Gregorio</creatorcontrib><creatorcontrib>Pini, Paula</creatorcontrib><creatorcontrib>Pedace, Paula</creatorcontrib><creatorcontrib>Tocalini, Pablo</creatorcontrib><creatorcontrib>Pérez Calvo, Eliana</creatorcontrib><creatorcontrib>Planells, Fernando</creatorcontrib><title>Mortality in Patients Requiring Prolonged Mechanical Ventilation: A Retrospective Cohort Study with Propensity Score Analysis</title><title>Revista americana de medicina respiratoria</title><addtitle>Rev. am. med. respir</addtitle><description><![CDATA[ABSTRACT Background: An increase has been observed in the number of patients requiring spe cialized care in mechanical ventilation weaning and rehabilitation centers (MVWRCs). Methods: An observational study with propensity score analysis was conducted on a 13- year cohort of patients in a MVWRC in Argentina. Predictors of mortality were analyzed. Results: Mortality assessed using the inverse probability of treatment weighting was as sociated with age [OR=1.037 (95% CI: 1.023-1.052), p<0.001], weaning from mechanical ventilation (MV) [OR=0.398 (95% CI: 0.282-0.560), p<0.001], decannulation [OR=0.059 (95% CI: 0.038-0.091), p<0.001], history of cardiovascular disease [OR=1.684 (95% CI: 1.146-2.474), p<0.001], pneumonia in non-chronic obstructive pulmonary disease (non-COPD) [OR=2.649 (95% CI: 1.631-4.302), p<0.001], and COPD [OR=0.477 (95% CI: 0.298-0.762), p=0.002]. Multiple logistic regression analysis in the propensity score-matched sample indicated that weaning from MV [OR=0.313 (95% CI: 0.137-0.715), p=0.006] and decannulation [OR=0.057 (95% CI: 0.021-0.155), p=<0.001] remained associated with lower mortal ity, whereas age [OR=1.056 (95% CI: 1.026-1.087), p=<0.001] remained a predictor associated with higher mortality. Conclusion: Mortality in patients requiring MV in a MVWRC was independently associ ated with older age, failed weaning from MV, and non-decannulation. It is very important to identify such predictors in order to plan attainable treatment goals.]]></description><subject>NEUROSCIENCES</subject><issn>1852-236X</issn><issn>1852-236X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNqVjzFPwzAQhS0EEhV0Zb4_0ODYTRrYqgrEUqkiqOoWGedornLtYjtABv47jsTAyvRu-O49fYzd5DwrykJWt14dfXb8al_v5kKesUleFWImZLk7_3NfsmkIB855viilrKoJ-147H5WhOABZ2KhIaGOAZ3zvyZPdw8Y74-weW1ij7pQlrQxsE0Qmwc7ewzLR0btwQh3pA2HlutQJdezbAT4pdmPHCW0YR2rtPMLSKjMECtfs4k2ZgNPfvGLZ48PL6mkWNKFxzcH1PqGhqUeFZlQQXMyTgEgOxUL---EH6Qdc0g</recordid><startdate>202401</startdate><enddate>202401</enddate><creator>Villalba, Darío</creator><creator>Díaz-Ballve, Ladislao</creator><creator>Scrigna, Mariana</creator><creator>Collins, Jessica</creator><creator>Matesa, Amelia</creator><creator>Áreas, Laura</creator><creator>Golfarini, Nicolás</creator><creator>Gil-Rossetti, Gregorio</creator><creator>Pini, Paula</creator><creator>Pedace, Paula</creator><creator>Tocalini, Pablo</creator><creator>Pérez Calvo, Eliana</creator><creator>Planells, Fernando</creator><general>Asociación Argentina de Medicina Respiratoria</general><scope>GPN</scope></search><sort><creationdate>202401</creationdate><title>Mortality in Patients Requiring Prolonged Mechanical Ventilation: A Retrospective Cohort Study with Propensity Score Analysis</title><author>Villalba, Darío ; Díaz-Ballve, Ladislao ; Scrigna, Mariana ; Collins, Jessica ; Matesa, Amelia ; Áreas, Laura ; Golfarini, Nicolás ; Gil-Rossetti, Gregorio ; Pini, Paula ; Pedace, Paula ; Tocalini, Pablo ; Pérez Calvo, Eliana ; Planells, Fernando</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-scielo_journals_S1852_236X20240002001573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>por</language><creationdate>2024</creationdate><topic>NEUROSCIENCES</topic><toplevel>online_resources</toplevel><creatorcontrib>Villalba, Darío</creatorcontrib><creatorcontrib>Díaz-Ballve, Ladislao</creatorcontrib><creatorcontrib>Scrigna, Mariana</creatorcontrib><creatorcontrib>Collins, Jessica</creatorcontrib><creatorcontrib>Matesa, Amelia</creatorcontrib><creatorcontrib>Áreas, Laura</creatorcontrib><creatorcontrib>Golfarini, Nicolás</creatorcontrib><creatorcontrib>Gil-Rossetti, Gregorio</creatorcontrib><creatorcontrib>Pini, Paula</creatorcontrib><creatorcontrib>Pedace, Paula</creatorcontrib><creatorcontrib>Tocalini, Pablo</creatorcontrib><creatorcontrib>Pérez Calvo, Eliana</creatorcontrib><creatorcontrib>Planells, Fernando</creatorcontrib><collection>SciELO</collection><jtitle>Revista americana de medicina respiratoria</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Villalba, Darío</au><au>Díaz-Ballve, Ladislao</au><au>Scrigna, Mariana</au><au>Collins, Jessica</au><au>Matesa, Amelia</au><au>Áreas, Laura</au><au>Golfarini, Nicolás</au><au>Gil-Rossetti, Gregorio</au><au>Pini, Paula</au><au>Pedace, Paula</au><au>Tocalini, Pablo</au><au>Pérez Calvo, Eliana</au><au>Planells, Fernando</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mortality in Patients Requiring Prolonged Mechanical Ventilation: A Retrospective Cohort Study with Propensity Score Analysis</atitle><jtitle>Revista americana de medicina respiratoria</jtitle><addtitle>Rev. am. med. respir</addtitle><date>2024-01</date><risdate>2024</risdate><volume>24</volume><issue>2</issue><spage>157</spage><epage>166</epage><pages>157-166</pages><issn>1852-236X</issn><eissn>1852-236X</eissn><abstract><![CDATA[ABSTRACT Background: An increase has been observed in the number of patients requiring spe cialized care in mechanical ventilation weaning and rehabilitation centers (MVWRCs). Methods: An observational study with propensity score analysis was conducted on a 13- year cohort of patients in a MVWRC in Argentina. Predictors of mortality were analyzed. Results: Mortality assessed using the inverse probability of treatment weighting was as sociated with age [OR=1.037 (95% CI: 1.023-1.052), p<0.001], weaning from mechanical ventilation (MV) [OR=0.398 (95% CI: 0.282-0.560), p<0.001], decannulation [OR=0.059 (95% CI: 0.038-0.091), p<0.001], history of cardiovascular disease [OR=1.684 (95% CI: 1.146-2.474), p<0.001], pneumonia in non-chronic obstructive pulmonary disease (non-COPD) [OR=2.649 (95% CI: 1.631-4.302), p<0.001], and COPD [OR=0.477 (95% CI: 0.298-0.762), p=0.002]. Multiple logistic regression analysis in the propensity score-matched sample indicated that weaning from MV [OR=0.313 (95% CI: 0.137-0.715), p=0.006] and decannulation [OR=0.057 (95% CI: 0.021-0.155), p=<0.001] remained associated with lower mortal ity, whereas age [OR=1.056 (95% CI: 1.026-1.087), p=<0.001] remained a predictor associated with higher mortality. Conclusion: Mortality in patients requiring MV in a MVWRC was independently associ ated with older age, failed weaning from MV, and non-decannulation. It is very important to identify such predictors in order to plan attainable treatment goals.]]></abstract><pub>Asociación Argentina de Medicina Respiratoria</pub><doi>10.56538/ramr.mxdb9423</doi><oa>free_for_read</oa></addata></record> |
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| title | Mortality in Patients Requiring Prolonged Mechanical Ventilation: A Retrospective Cohort Study with Propensity Score Analysis |
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