Outcomes of Elderly Patients Undergoing Emergency Surgery for Complicated Colorectal Cancer: A Retrospective Cohort Study

Colorectal cancer is one of the most frequent types of malignant neoplasms. Age is a risk factor for this disease, with 75% of cases diagnosed in patients older than 65 years. Complications such as obstruction, hemorrhage, and perforation are present in more than one-third of cases and require emerg...

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Veröffentlicht in:Clinics (São Paulo, Brazil) Brazil), 2019, Vol.74, p.e1074-e1074, Article e1074
Hauptverfasser: Menegozzo, Carlos Augusto Metidieri, Teixeira-Júnior, Frederico, do Couto-Netto, Sérgio Dias, Martins-Júnior, Octacílio, de Oliveira Bernini, Celso, Utiyama, Edivaldo Massazo
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container_title Clinics (São Paulo, Brazil)
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creator Menegozzo, Carlos Augusto Metidieri
Teixeira-Júnior, Frederico
do Couto-Netto, Sérgio Dias
Martins-Júnior, Octacílio
de Oliveira Bernini, Celso
Utiyama, Edivaldo Massazo
description Colorectal cancer is one of the most frequent types of malignant neoplasms. Age is a risk factor for this disease, with 75% of cases diagnosed in patients older than 65 years. Complications such as obstruction, hemorrhage, and perforation are present in more than one-third of cases and require emergency treatment. We aim to analyze the profile of elderly patients undergoing surgery for complicated colorectal cancer, and to evaluate factors related to worse short-term prognosis. A retrospective analysis of patients who underwent emergency surgical treatment for complicated colorectal cancer was performed. Demographics, clinical, radiological and histological data were collected. Sixty-seven patients were analyzed. The median age was 72 years, and almost half (46%) of the patients were female. Obstruction was the most prevalent complication at initial presentation (72%). The most common sites of neoplasia were the left and sigmoid colon in 22 patients (32.8%), and the right colon in 17 patients (25.4%). Resection was performed in 88% of cases, followed by primary anastomosis in almost half. The most frequent clinical stages were II (48%) and III (22%). Forty-three patients (65.7%) had some form of postoperative complication. Clavien-Dindo grades 1, 2, and 4, were the most frequent. Complete oncologic resection was observed in 80% of the cases. The thirty-day mortality rate was 10.4%. Advanced age was associated with worse morbidity and mortality. Elderly patients with complicated colorectal cancer undergoing emergency surgery have high morbidity and mortality rates. Advanced age is significantly associated with worse outcomes.
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Resection was performed in 88% of cases, followed by primary anastomosis in almost half. The most frequent clinical stages were II (48%) and III (22%). Forty-three patients (65.7%) had some form of postoperative complication. Clavien-Dindo grades 1, 2, and 4, were the most frequent. Complete oncologic resection was observed in 80% of the cases. The thirty-day mortality rate was 10.4%. Advanced age was associated with worse morbidity and mortality. Elderly patients with complicated colorectal cancer undergoing emergency surgery have high morbidity and mortality rates. 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numerical data</topic><topic>Length of Stay</topic><topic>Male</topic><topic>MEDICINE, GENERAL &amp; INTERNAL</topic><topic>Middle Aged</topic><topic>Neoplasm Staging</topic><topic>Original</topic><topic>Postoperative Complications</topic><topic>Postoperative Complications - mortality</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Statistics, Nonparametric</topic><topic>Surgical Oncology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Menegozzo, Carlos Augusto Metidieri</creatorcontrib><creatorcontrib>Teixeira-Júnior, Frederico</creatorcontrib><creatorcontrib>do Couto-Netto, Sérgio Dias</creatorcontrib><creatorcontrib>Martins-Júnior, Octacílio</creatorcontrib><creatorcontrib>de Oliveira Bernini, Celso</creatorcontrib><creatorcontrib>Utiyama, Edivaldo Massazo</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>SciELO</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Clinics (São Paulo, Brazil)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Menegozzo, Carlos Augusto Metidieri</au><au>Teixeira-Júnior, Frederico</au><au>do Couto-Netto, Sérgio Dias</au><au>Martins-Júnior, Octacílio</au><au>de Oliveira Bernini, Celso</au><au>Utiyama, Edivaldo Massazo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outcomes of Elderly Patients Undergoing Emergency Surgery for Complicated Colorectal Cancer: A Retrospective Cohort Study</atitle><jtitle>Clinics (São Paulo, Brazil)</jtitle><addtitle>Clinics (Sao Paulo)</addtitle><date>2019</date><risdate>2019</risdate><volume>74</volume><spage>e1074</spage><epage>e1074</epage><pages>e1074-e1074</pages><artnum>e1074</artnum><issn>1807-5932</issn><issn>1980-5322</issn><eissn>1980-5322</eissn><abstract>Colorectal cancer is one of the most frequent types of malignant neoplasms. Age is a risk factor for this disease, with 75% of cases diagnosed in patients older than 65 years. Complications such as obstruction, hemorrhage, and perforation are present in more than one-third of cases and require emergency treatment. We aim to analyze the profile of elderly patients undergoing surgery for complicated colorectal cancer, and to evaluate factors related to worse short-term prognosis. A retrospective analysis of patients who underwent emergency surgical treatment for complicated colorectal cancer was performed. Demographics, clinical, radiological and histological data were collected. Sixty-seven patients were analyzed. The median age was 72 years, and almost half (46%) of the patients were female. Obstruction was the most prevalent complication at initial presentation (72%). The most common sites of neoplasia were the left and sigmoid colon in 22 patients (32.8%), and the right colon in 17 patients (25.4%). Resection was performed in 88% of cases, followed by primary anastomosis in almost half. The most frequent clinical stages were II (48%) and III (22%). Forty-three patients (65.7%) had some form of postoperative complication. Clavien-Dindo grades 1, 2, and 4, were the most frequent. Complete oncologic resection was observed in 80% of the cases. The thirty-day mortality rate was 10.4%. Advanced age was associated with worse morbidity and mortality. Elderly patients with complicated colorectal cancer undergoing emergency surgery have high morbidity and mortality rates. Advanced age is significantly associated with worse outcomes.</abstract><cop>Brazil</cop><pub>Elsevier España, S.L.U</pub><pmid>31433041</pmid><doi>10.6061/clinics/2019/e1074</doi><orcidid>https://orcid.org/0000-0002-8453-7184</orcidid><orcidid>https://orcid.org/0000-0003-3572-8977</orcidid><oa>free_for_read</oa></addata></record>
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subjects Age Factors
Aged
Aged, 80 and over
Brazil
Colorectal Neoplasms
Colorectal Neoplasms - complications
Colorectal Neoplasms - mortality
Colorectal Neoplasms - pathology
Colorectal Neoplasms - surgery
Colorectal Surgery
Comorbidity
Elderly
Emergency Treatment
Emergency Treatment - mortality
Female
General Surgery
Humans
Intensive Care Units - statistics & numerical data
Length of Stay
Male
MEDICINE, GENERAL & INTERNAL
Middle Aged
Neoplasm Staging
Original
Postoperative Complications
Postoperative Complications - mortality
Prognosis
Retrospective Studies
Risk Factors
Statistics, Nonparametric
Surgical Oncology
title Outcomes of Elderly Patients Undergoing Emergency Surgery for Complicated Colorectal Cancer: A Retrospective Cohort Study
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