Evaluation of the maxillary and mandibular implant failure rate in patients with type 1 and type 2 diabetes: a systematic review and meta-analysis

Aim: The present study evaluated maxillary and mandibular implant failure rates in patients with type 1 diabetes and type 2 diabetes. Methods: All articles published in international databases such as PubMed, Scopus, Science Direct, ISI Web of knowledge, and Embase between 2016 to July 2022 are included. 95% confidence interval on odds ratio and mean differences were done with a fixed effect model. Meta-analysis data collected from selected studies were performed using Stata/MP.V17 software. Results: In the initial review, duplicate studies were eliminated, abstracts of 1311 studies were reviewed, two authors reviewed the full text of 243 studies, and finally, 37 studies were selected. The odds ratio of implant failure rate between diabetic and non-diabetic patients was 5.31 (OR, 95% CI 5.06, 5.56; p=00). The mean difference in marginal bone loss between diabetic and nondiabetic patients was 1.63 (MD, 95% CI 0.89, 2.37; p=0.00). Conclusion: Based on the findings of the present study, the survival rate of implants in patients with diabetes was lower than in non-diabetic patients. Also, marginal bone loss was higher in patients with diabetes than in non-diabetic patients.