Normal Values of T, B and NK Lymphocyte Subpopulations in Peripheral Blood of Healthy Cuban Adults

INTRODUCTION Quantification of lymphocyte subpopulations is useful for evaluating immune response in states of health and disease, including immunodeficiencies, autoimmunity, infections and cancer. Studies have found that concentrations and proportions of different cell subpopulations vary with geog...

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Veröffentlicht in:MEDICC review 2019-04, Vol.21 (2-3), p.16-21
Hauptverfasser: Kokuina, Elena, Breff-Fonseca, Martha C, Villegas-Valverde, Carlos A, Mora-Díaz, Isabel
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Sprache:eng
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Zusammenfassung:INTRODUCTION Quantification of lymphocyte subpopulations is useful for evaluating immune response in states of health and disease, including immunodeficiencies, autoimmunity, infections and cancer. Studies have found that concentrations and proportions of different cell subpopulations vary with geographic location, age, sex and ethnicity. Knowing the normal values of these cells and their variation in healthy populations will contribute to improved clinical practice and scientific research. OBJECTIVE Estimate normal absolute concentrations and percentages of the most abundant lymphocyte subpopulations in peripheral blood and their relation to sex and age. METHODS A cross-sectional analysis was conducted in 129 healthy adults, 61 men and 68 women aged 18-80 years; 89 aged
ISSN:1555-7960
1527-3172
1527-3172
DOI:10.37757/MR2019.V21.N2-3.5