Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine
The brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports t...
Gespeichert in:
| Veröffentlicht in: | Brazilian journal of biology 2012-08, Vol.72 (3), p.505-509 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 509 |
|---|---|
| container_issue | 3 |
| container_start_page | 505 |
| container_title | Brazilian journal of biology |
| container_volume | 72 |
| creator | Arcanjo, D D R Albuquerque, A C M Melo-Neto, B Santana, L C L R Medeiros, M G F Citó, Amgl |
| description | The brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports the bioactivity of ethanol extracts from seven medicinal plants from the Northeast of Brazil (Acmella uliginosa, Ageratum conyzoides, Eugenia uniflora, Plectranthus neochilus, Moringa oleifera, Justicia pectoralis and Equisetum sp.) against Artemia salina. Biological activity was evaluated for extracts at 1, 10, 100, and 1000 µg/mL in triplicate, and the mean lethal concentration values (LC50) were obtained by probit analysis. The species Acmella uliginosa showed the highest bioactivity, and its flower extract was more active than its leaf extract. |
| doi_str_mv | 10.1590/S1519-69842012000300013 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_sciel</sourceid><recordid>TN_cdi_scielo_journals_S1519_69842012000300013</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><scielo_id>S1519_69842012000300013</scielo_id><sourcerecordid>1041324818</sourcerecordid><originalsourceid>FETCH-LOGICAL-c385t-f34640e920a29c99a61c8b23736d586acd6b500d840fa327443274d8978bfb5b3</originalsourceid><addsrcrecordid>eNp9UclOwzAQtRCI_RfARy4p3pLYR0BsUgUH4BxNHAcMblxspxJ8PYa2XJA4zKLRe7O8QeiYkgktFTl9oCVVRaWkYIQyQgjPRvkG2qVVLQvB63Iz52vQDtqL8ZUQVhIut9EOY0oRyeguSufWg052YdMHNgtwIyTrBwzPYIeY8FlIZmYBR3B2ADw1oF-w7_HMdFbnisNzB0OKeIymw3bA5wE-rbMw4Dsf0ouBmEwYcO_d25pkDtBWDy6aw1XcR09Xl48XN8X0_vr24mxaaC7LVPRcVIIYxQgwpZWCimrZMl7zqitlBbqr2pKQTgrSA2e1EN-uk6qWbd-WLd9Hk2XfqK1xvnn1Y8grx-ZHvuaPfJlwsiTMg38fTUzNzEZtXD7R-DE2lAjKmZBUZmi9hOrgYwymb-bBziB8ZFDz_aN_hhythoxtVuSXt34K_wIVhIqm</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1041324818</pqid></control><display><type>article</type><title>Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Arcanjo, D D R ; Albuquerque, A C M ; Melo-Neto, B ; Santana, L C L R ; Medeiros, M G F ; Citó, Amgl</creator><creatorcontrib>Arcanjo, D D R ; Albuquerque, A C M ; Melo-Neto, B ; Santana, L C L R ; Medeiros, M G F ; Citó, Amgl</creatorcontrib><description>The brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports the bioactivity of ethanol extracts from seven medicinal plants from the Northeast of Brazil (Acmella uliginosa, Ageratum conyzoides, Eugenia uniflora, Plectranthus neochilus, Moringa oleifera, Justicia pectoralis and Equisetum sp.) against Artemia salina. Biological activity was evaluated for extracts at 1, 10, 100, and 1000 µg/mL in triplicate, and the mean lethal concentration values (LC50) were obtained by probit analysis. The species Acmella uliginosa showed the highest bioactivity, and its flower extract was more active than its leaf extract.</description><identifier>ISSN: 1519-6984</identifier><identifier>ISSN: 1678-4375</identifier><identifier>EISSN: 1678-4375</identifier><identifier>EISSN: 1519-6984</identifier><identifier>DOI: 10.1590/S1519-69842012000300013</identifier><identifier>PMID: 22990821</identifier><language>eng</language><publisher>Brazil: Instituto Internacional de Ecologia</publisher><subject>Animals ; Artemia - drug effects ; Biological Assay ; BIOLOGY ; Dose-Response Relationship, Drug ; Lethal Dose 50 ; Plant Extracts - pharmacology ; Plants, Medicinal - chemistry ; Plants, Medicinal - classification</subject><ispartof>Brazilian journal of biology, 2012-08, Vol.72 (3), p.505-509</ispartof><rights>This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c385t-f34640e920a29c99a61c8b23736d586acd6b500d840fa327443274d8978bfb5b3</citedby><cites>FETCH-LOGICAL-c385t-f34640e920a29c99a61c8b23736d586acd6b500d840fa327443274d8978bfb5b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,864,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22990821$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Arcanjo, D D R</creatorcontrib><creatorcontrib>Albuquerque, A C M</creatorcontrib><creatorcontrib>Melo-Neto, B</creatorcontrib><creatorcontrib>Santana, L C L R</creatorcontrib><creatorcontrib>Medeiros, M G F</creatorcontrib><creatorcontrib>Citó, Amgl</creatorcontrib><title>Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine</title><title>Brazilian journal of biology</title><addtitle>Braz J Biol</addtitle><description>The brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports the bioactivity of ethanol extracts from seven medicinal plants from the Northeast of Brazil (Acmella uliginosa, Ageratum conyzoides, Eugenia uniflora, Plectranthus neochilus, Moringa oleifera, Justicia pectoralis and Equisetum sp.) against Artemia salina. Biological activity was evaluated for extracts at 1, 10, 100, and 1000 µg/mL in triplicate, and the mean lethal concentration values (LC50) were obtained by probit analysis. The species Acmella uliginosa showed the highest bioactivity, and its flower extract was more active than its leaf extract.</description><subject>Animals</subject><subject>Artemia - drug effects</subject><subject>Biological Assay</subject><subject>BIOLOGY</subject><subject>Dose-Response Relationship, Drug</subject><subject>Lethal Dose 50</subject><subject>Plant Extracts - pharmacology</subject><subject>Plants, Medicinal - chemistry</subject><subject>Plants, Medicinal - classification</subject><issn>1519-6984</issn><issn>1678-4375</issn><issn>1678-4375</issn><issn>1519-6984</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UclOwzAQtRCI_RfARy4p3pLYR0BsUgUH4BxNHAcMblxspxJ8PYa2XJA4zKLRe7O8QeiYkgktFTl9oCVVRaWkYIQyQgjPRvkG2qVVLQvB63Iz52vQDtqL8ZUQVhIut9EOY0oRyeguSufWg052YdMHNgtwIyTrBwzPYIeY8FlIZmYBR3B2ADw1oF-w7_HMdFbnisNzB0OKeIymw3bA5wE-rbMw4Dsf0ouBmEwYcO_d25pkDtBWDy6aw1XcR09Xl48XN8X0_vr24mxaaC7LVPRcVIIYxQgwpZWCimrZMl7zqitlBbqr2pKQTgrSA2e1EN-uk6qWbd-WLd9Hk2XfqK1xvnn1Y8grx-ZHvuaPfJlwsiTMg38fTUzNzEZtXD7R-DE2lAjKmZBUZmi9hOrgYwymb-bBziB8ZFDz_aN_hhythoxtVuSXt34K_wIVhIqm</recordid><startdate>201208</startdate><enddate>201208</enddate><creator>Arcanjo, D D R</creator><creator>Albuquerque, A C M</creator><creator>Melo-Neto, B</creator><creator>Santana, L C L R</creator><creator>Medeiros, M G F</creator><creator>Citó, Amgl</creator><general>Instituto Internacional de Ecologia</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>GPN</scope></search><sort><creationdate>201208</creationdate><title>Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine</title><author>Arcanjo, D D R ; Albuquerque, A C M ; Melo-Neto, B ; Santana, L C L R ; Medeiros, M G F ; Citó, Amgl</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c385t-f34640e920a29c99a61c8b23736d586acd6b500d840fa327443274d8978bfb5b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animals</topic><topic>Artemia - drug effects</topic><topic>Biological Assay</topic><topic>BIOLOGY</topic><topic>Dose-Response Relationship, Drug</topic><topic>Lethal Dose 50</topic><topic>Plant Extracts - pharmacology</topic><topic>Plants, Medicinal - chemistry</topic><topic>Plants, Medicinal - classification</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arcanjo, D D R</creatorcontrib><creatorcontrib>Albuquerque, A C M</creatorcontrib><creatorcontrib>Melo-Neto, B</creatorcontrib><creatorcontrib>Santana, L C L R</creatorcontrib><creatorcontrib>Medeiros, M G F</creatorcontrib><creatorcontrib>Citó, Amgl</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>SciELO</collection><jtitle>Brazilian journal of biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Arcanjo, D D R</au><au>Albuquerque, A C M</au><au>Melo-Neto, B</au><au>Santana, L C L R</au><au>Medeiros, M G F</au><au>Citó, Amgl</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine</atitle><jtitle>Brazilian journal of biology</jtitle><addtitle>Braz J Biol</addtitle><date>2012-08</date><risdate>2012</risdate><volume>72</volume><issue>3</issue><spage>505</spage><epage>509</epage><pages>505-509</pages><issn>1519-6984</issn><issn>1678-4375</issn><eissn>1678-4375</eissn><eissn>1519-6984</eissn><abstract>The brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports the bioactivity of ethanol extracts from seven medicinal plants from the Northeast of Brazil (Acmella uliginosa, Ageratum conyzoides, Eugenia uniflora, Plectranthus neochilus, Moringa oleifera, Justicia pectoralis and Equisetum sp.) against Artemia salina. Biological activity was evaluated for extracts at 1, 10, 100, and 1000 µg/mL in triplicate, and the mean lethal concentration values (LC50) were obtained by probit analysis. The species Acmella uliginosa showed the highest bioactivity, and its flower extract was more active than its leaf extract.</abstract><cop>Brazil</cop><pub>Instituto Internacional de Ecologia</pub><pmid>22990821</pmid><doi>10.1590/S1519-69842012000300013</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1519-6984 |
| ispartof | Brazilian journal of biology, 2012-08, Vol.72 (3), p.505-509 |
| issn | 1519-6984 1678-4375 1678-4375 1519-6984 |
| language | eng |
| recordid | cdi_scielo_journals_S1519_69842012000300013 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Animals Artemia - drug effects Biological Assay BIOLOGY Dose-Response Relationship, Drug Lethal Dose 50 Plant Extracts - pharmacology Plants, Medicinal - chemistry Plants, Medicinal - classification |
| title | Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T10%3A46%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_sciel&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Bioactivity%20evaluation%20against%20Artemia%20salina%20Leach%20of%20medicinal%20plants%20used%20in%20Brazilian%20Northeastern%20folk%20medicine&rft.jtitle=Brazilian%20journal%20of%20biology&rft.au=Arcanjo,%20D%20D%20R&rft.date=2012-08&rft.volume=72&rft.issue=3&rft.spage=505&rft.epage=509&rft.pages=505-509&rft.issn=1519-6984&rft.eissn=1678-4375&rft_id=info:doi/10.1590/S1519-69842012000300013&rft_dat=%3Cproquest_sciel%3E1041324818%3C/proquest_sciel%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1041324818&rft_id=info:pmid/22990821&rft_scielo_id=S1519_69842012000300013&rfr_iscdi=true |