Correlation between serum tumor necrosis factor alpha levels and clinical severity of tuberculosis

This study verified the correlation between the serum levels of TNF alpha and different clinical forms of tuberculosis. We described a group of 24 patients presenting several clinical forms of tuberculosis and a control group of 13 healthy individuals. The levels of TNF alpha were measured by bioass...

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Veröffentlicht in:The Brazilian journal of infectious diseases 2008-06, Vol.12 (3), p.226-233
Hauptverfasser: Andrade Júnior, Dahir Ramos de, Santos, Sânia Alves dos, Castro, Isac de, Andrade, Dahir Ramos de
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Sprache:eng
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Zusammenfassung:This study verified the correlation between the serum levels of TNF alpha and different clinical forms of tuberculosis. We described a group of 24 patients presenting several clinical forms of tuberculosis and a control group of 13 healthy individuals. The levels of TNF alpha were measured by bioassay method. The levels of TNF-alpha had significant differences between the tuberculosis and control groups. The patients with abnormal chest X-Ray findings had higher TNF alpha levels (15328.48 +/- 4602.19 pg/mL) when compared to patients with normal X-Rays (3353.18 +/- 1495.29 pg/mL) (p
ISSN:1413-8670
1678-4391
1678-4391
1413-8670
DOI:10.1590/s1413-86702008000300013