Gallbladder leiomyoma in absence of immune system disorders: an unusual diagnosis
Mesenchymal neoplasms of the gallbladder are rare and in particular leiomyomas of the gallbladder have been rarely reported, all of them in patients with immune system disorders.This is the first report in Spanish of a 23-year-old female patient with a gallbladder leiomyoma without associated immuno...
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Veröffentlicht in: | Revista española de enfermedades digestivas 2012-07, Vol.104 (7), p.382-384 |
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creator | Segura-Sampedro, Juan José Alamo-Martínez, José María Cañete-Gómez, Jesús Suárez-Artacho, Gonzalo González-Cantón, Joaquín Roberto Gómez-Bravo, Miguel Ángel Padillo-Ruiz, Francisco Javier |
description | Mesenchymal neoplasms of the gallbladder are rare and in particular leiomyomas of the gallbladder have been rarely reported, all of them in patients with immune system disorders.This is the first report in Spanish of a 23-year-old female patient with a gallbladder leiomyoma without associated immunodeficiency. The patient lacks a previous history of uterine leiomyoma or any other form of neoplasm. She refers several episodes of epygastralgia. A hydatic cyst led to an initial diagnosis and the gallbladder was removed by means of simple cholecystectomy. The abnormal macroscopic aspect of the sample prompted intraoperative biopsy which revealed a benign gallbladder angiomyoma. Subsequent immunohistochemical analysis of the resected sample yielded the diagnosis of intramural endocavitary leiomyoma negative for EBV and C-kit / CD-117. The patient has good general condition and remains asymptomatic 15 months after surgery. |
doi_str_mv | 10.4321/S1130-01082012000700009 |
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The patient lacks a previous history of uterine leiomyoma or any other form of neoplasm. She refers several episodes of epygastralgia. A hydatic cyst led to an initial diagnosis and the gallbladder was removed by means of simple cholecystectomy. The abnormal macroscopic aspect of the sample prompted intraoperative biopsy which revealed a benign gallbladder angiomyoma. Subsequent immunohistochemical analysis of the resected sample yielded the diagnosis of intramural endocavitary leiomyoma negative for EBV and C-kit / CD-117. The patient has good general condition and remains asymptomatic 15 months after surgery.</description><identifier>ISSN: 1130-0108</identifier><identifier>DOI: 10.4321/S1130-01082012000700009</identifier><identifier>PMID: 22849501</identifier><language>eng</language><publisher>Spain: Sociedad Española de Patología Digestiva</publisher><subject>Female ; Gallbladder Neoplasms - diagnosis ; Gallbladder Neoplasms - immunology ; Gastroenterology & Hepatology ; Geriatrics & Gerontology ; Humans ; Infectious Diseases ; Leiomyoma - diagnosis ; Leiomyoma - immunology ; Oncology ; Pathology ; Pharmacology & Pharmacy ; Radiology, Nuclear Medicine & Medical Imaging ; Surgery ; Young Adult</subject><ispartof>Revista española de enfermedades digestivas, 2012-07, Vol.104 (7), p.382-384</ispartof><rights>This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c331t-e5eb013be7e847d72761604435342c9c296857af8da31e910c8236ec26d0c69d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,864,885,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22849501$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Segura-Sampedro, Juan José</creatorcontrib><creatorcontrib>Alamo-Martínez, José María</creatorcontrib><creatorcontrib>Cañete-Gómez, Jesús</creatorcontrib><creatorcontrib>Suárez-Artacho, Gonzalo</creatorcontrib><creatorcontrib>González-Cantón, Joaquín Roberto</creatorcontrib><creatorcontrib>Gómez-Bravo, Miguel Ángel</creatorcontrib><creatorcontrib>Padillo-Ruiz, Francisco Javier</creatorcontrib><title>Gallbladder leiomyoma in absence of immune system disorders: an unusual diagnosis</title><title>Revista española de enfermedades digestivas</title><addtitle>Rev Esp Enferm Dig</addtitle><description>Mesenchymal neoplasms of the gallbladder are rare and in particular leiomyomas of the gallbladder have been rarely reported, all of them in patients with immune system disorders.This is the first report in Spanish of a 23-year-old female patient with a gallbladder leiomyoma without associated immunodeficiency. The patient lacks a previous history of uterine leiomyoma or any other form of neoplasm. She refers several episodes of epygastralgia. A hydatic cyst led to an initial diagnosis and the gallbladder was removed by means of simple cholecystectomy. The abnormal macroscopic aspect of the sample prompted intraoperative biopsy which revealed a benign gallbladder angiomyoma. Subsequent immunohistochemical analysis of the resected sample yielded the diagnosis of intramural endocavitary leiomyoma negative for EBV and C-kit / CD-117. The patient has good general condition and remains asymptomatic 15 months after surgery.</description><subject>Female</subject><subject>Gallbladder Neoplasms - diagnosis</subject><subject>Gallbladder Neoplasms - immunology</subject><subject>Gastroenterology & Hepatology</subject><subject>Geriatrics & Gerontology</subject><subject>Humans</subject><subject>Infectious Diseases</subject><subject>Leiomyoma - diagnosis</subject><subject>Leiomyoma - immunology</subject><subject>Oncology</subject><subject>Pathology</subject><subject>Pharmacology & Pharmacy</subject><subject>Radiology, Nuclear Medicine & Medical Imaging</subject><subject>Surgery</subject><subject>Young Adult</subject><issn>1130-0108</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhnNQbK3-Bc3Ry9bJx355k6JVEETU85LNzsqW7KZmmkP_vautvQgewkDmeeaFl7FLAXOtpLh-FUJBAgIKCUICQD4-KI_Y9LCYsFOiFYBWWSpP2ETKQpcpiCl7WRrnameaBgN32Pl-63vDu4GbmnCwyH3Lu76PA3La0gZ73nTkw4jTDTcDj0OkaNz4az4GTx2dsePWOMLz_Zyx9_u7t8VD8vS8fFzcPiVWKbFJMMUahKoxx0LnTS7zTGSgtUqVlra0ssyKNDdt0RglsBRgC6kytDJrwGZlo2ZsvrtLtkPnq5WPYRgDq58-qj99jMLVTlgH_xmRNlXfkUXnzIA-UjUKQistSjmi-Q61wRMFbKt16HoTtiNUfZf-T8jFPiTWPTYH77dx9QV-0ntO</recordid><startdate>201207</startdate><enddate>201207</enddate><creator>Segura-Sampedro, Juan José</creator><creator>Alamo-Martínez, José María</creator><creator>Cañete-Gómez, Jesús</creator><creator>Suárez-Artacho, Gonzalo</creator><creator>González-Cantón, Joaquín Roberto</creator><creator>Gómez-Bravo, Miguel Ángel</creator><creator>Padillo-Ruiz, Francisco Javier</creator><general>Sociedad Española de Patología Digestiva</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>GPN</scope></search><sort><creationdate>201207</creationdate><title>Gallbladder leiomyoma in absence of immune system disorders: an unusual diagnosis</title><author>Segura-Sampedro, Juan José ; Alamo-Martínez, José María ; Cañete-Gómez, Jesús ; Suárez-Artacho, Gonzalo ; González-Cantón, Joaquín Roberto ; Gómez-Bravo, Miguel Ángel ; Padillo-Ruiz, Francisco Javier</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c331t-e5eb013be7e847d72761604435342c9c296857af8da31e910c8236ec26d0c69d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Female</topic><topic>Gallbladder Neoplasms - diagnosis</topic><topic>Gallbladder Neoplasms - immunology</topic><topic>Gastroenterology & Hepatology</topic><topic>Geriatrics & Gerontology</topic><topic>Humans</topic><topic>Infectious Diseases</topic><topic>Leiomyoma - diagnosis</topic><topic>Leiomyoma - immunology</topic><topic>Oncology</topic><topic>Pathology</topic><topic>Pharmacology & Pharmacy</topic><topic>Radiology, Nuclear Medicine & Medical Imaging</topic><topic>Surgery</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Segura-Sampedro, Juan José</creatorcontrib><creatorcontrib>Alamo-Martínez, José María</creatorcontrib><creatorcontrib>Cañete-Gómez, Jesús</creatorcontrib><creatorcontrib>Suárez-Artacho, Gonzalo</creatorcontrib><creatorcontrib>González-Cantón, Joaquín Roberto</creatorcontrib><creatorcontrib>Gómez-Bravo, Miguel Ángel</creatorcontrib><creatorcontrib>Padillo-Ruiz, Francisco Javier</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>SciELO</collection><jtitle>Revista española de enfermedades digestivas</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Segura-Sampedro, Juan José</au><au>Alamo-Martínez, José María</au><au>Cañete-Gómez, Jesús</au><au>Suárez-Artacho, Gonzalo</au><au>González-Cantón, Joaquín Roberto</au><au>Gómez-Bravo, Miguel Ángel</au><au>Padillo-Ruiz, Francisco Javier</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gallbladder leiomyoma in absence of immune system disorders: an unusual diagnosis</atitle><jtitle>Revista española de enfermedades digestivas</jtitle><addtitle>Rev Esp Enferm Dig</addtitle><date>2012-07</date><risdate>2012</risdate><volume>104</volume><issue>7</issue><spage>382</spage><epage>384</epage><pages>382-384</pages><issn>1130-0108</issn><abstract>Mesenchymal neoplasms of the gallbladder are rare and in particular leiomyomas of the gallbladder have been rarely reported, all of them in patients with immune system disorders.This is the first report in Spanish of a 23-year-old female patient with a gallbladder leiomyoma without associated immunodeficiency. The patient lacks a previous history of uterine leiomyoma or any other form of neoplasm. She refers several episodes of epygastralgia. A hydatic cyst led to an initial diagnosis and the gallbladder was removed by means of simple cholecystectomy. The abnormal macroscopic aspect of the sample prompted intraoperative biopsy which revealed a benign gallbladder angiomyoma. Subsequent immunohistochemical analysis of the resected sample yielded the diagnosis of intramural endocavitary leiomyoma negative for EBV and C-kit / CD-117. The patient has good general condition and remains asymptomatic 15 months after surgery.</abstract><cop>Spain</cop><pub>Sociedad Española de Patología Digestiva</pub><pmid>22849501</pmid><doi>10.4321/S1130-01082012000700009</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
subjects | Female Gallbladder Neoplasms - diagnosis Gallbladder Neoplasms - immunology Gastroenterology & Hepatology Geriatrics & Gerontology Humans Infectious Diseases Leiomyoma - diagnosis Leiomyoma - immunology Oncology Pathology Pharmacology & Pharmacy Radiology, Nuclear Medicine & Medical Imaging Surgery Young Adult |
title | Gallbladder leiomyoma in absence of immune system disorders: an unusual diagnosis |
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