Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding
to determine the independent predictors of in-hospital death of Hispanic patients with nonvariceal upper gastrointestinal bleeding (NVUGB). prospective and observational trial. in a period between 2000 and 2009, all patients with NVUGB admitted to our hospital were studied. Demographical and clinica...
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| Veröffentlicht in: | Revista española de enfermedades digestivas 2011-04, Vol.103 (4), p.196-203 |
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| creator | González-González, José Alberto Vázquez-Elizondo, Genaro García-Compeán, Diego Gaytán-Torres, Juan Obed Flores-Rendón, Ángel Ricardo Jáquez-Quintana, Joel Omar Garza-Galindo, Aldo Azael Cárdenas-Sandoval, Martha Graciela Maldonado-Garza, Héctor Jesús |
| description | to determine the independent predictors of in-hospital death of Hispanic patients with nonvariceal upper gastrointestinal bleeding (NVUGB).
prospective and observational trial.
in a period between 2000 and 2009, all patients with NVUGB admitted to our hospital were studied. Demographical and clinical characteristics, endoscopic findings and laboratory tests were evaluated χ² and Mann-Whitney U analyses were per-formed for comparisons, and binary logistic regression was employed to identify independent predictors of in-hospital mortality.
1,067 patients were included, 65% male with a mean age of 58.8 years. Mean number of comorbidities per patient was 1.6 ± 0.76. The most frequent cause of bleeding were gastric and duodenal ulcers (55.4%); 278 patients (25.8%) received endoscopic treatment of which 69.1% had combined therapy. Rebleeding occurred in 36 patients (3.4%) of which 50% died. In-hospital mortality was 10.2%, of which only 3.1% was associated to bleeding. When comparing causes of death among patients with and without comorbidities, only hypovolemic shock was found significative (48.3 vs. 25%; p = 0.020). Binary logistic regression found that the number of comorbidities, Rockall scale score; serum albumin < 2.6 g/dL on admission; rebleeding and length of hospital stay were independent risk factors of in-hospital mortality.
the number of comorbidities, the Rockall scales core, an albumin level < 2.6 g/dL, the presence of rebleeding and hospital stay were predictors of in-hospital mortality in patients with NVUGB. |
| doi_str_mv | 10.4321/S1130-01082011000400005 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_sciel</sourceid><recordid>TN_cdi_scielo_journals_S1130_01082011000400005</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><scielo_id>S1130_01082011000400005</scielo_id><sourcerecordid>872439474</sourcerecordid><originalsourceid>FETCH-LOGICAL-c454t-d20b604af8b176668497148fb59ffbdba3e0e18aa8ae2666013e9b63f66ff7573</originalsourceid><addsrcrecordid>eNp9UctOwzAQ9AFES-EXIDdOKXbs2M4RVbykSiAB58hO7NZVYgfbAfXvMbT0gsRhNdLOzO5qB4BLBOcEF-j6BSEMc4ggLyBCEEKSCpZHYHogJuA0hE1iMC2LEzApUFlQzvAUiGevWtNE50PmdGZsvnZhMFF0We98AhO3qZsNIhplY8g-TVxn1tn8Q3jTqKQbh0H5bCVC9M7YqEI0NrVlp9JkuzoDx1p0QZ3vcQbe7m5fFw_58un-cXGzzBtSkpi3BZQUEqG5RIxSyknFEOFalpXWspUCK6gQF4ILVSQeIqwqSbGmVGtWMjwD893c0BjVuXrjRp_uCPXPf-o__0mGq51h8O59TGfXvQmN6jphlRtDzVlBcEUYSUq2UzbeheCVrgdveuG3NYL1dwb_7LjY7xhlr9qD7zcA_AVcK4K4</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>872439474</pqid></control><display><type>article</type><title>Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>González-González, José Alberto ; Vázquez-Elizondo, Genaro ; García-Compeán, Diego ; Gaytán-Torres, Juan Obed ; Flores-Rendón, Ángel Ricardo ; Jáquez-Quintana, Joel Omar ; Garza-Galindo, Aldo Azael ; Cárdenas-Sandoval, Martha Graciela ; Maldonado-Garza, Héctor Jesús</creator><creatorcontrib>González-González, José Alberto ; Vázquez-Elizondo, Genaro ; García-Compeán, Diego ; Gaytán-Torres, Juan Obed ; Flores-Rendón, Ángel Ricardo ; Jáquez-Quintana, Joel Omar ; Garza-Galindo, Aldo Azael ; Cárdenas-Sandoval, Martha Graciela ; Maldonado-Garza, Héctor Jesús</creatorcontrib><description>to determine the independent predictors of in-hospital death of Hispanic patients with nonvariceal upper gastrointestinal bleeding (NVUGB).
prospective and observational trial.
in a period between 2000 and 2009, all patients with NVUGB admitted to our hospital were studied. Demographical and clinical characteristics, endoscopic findings and laboratory tests were evaluated χ² and Mann-Whitney U analyses were per-formed for comparisons, and binary logistic regression was employed to identify independent predictors of in-hospital mortality.
1,067 patients were included, 65% male with a mean age of 58.8 years. Mean number of comorbidities per patient was 1.6 ± 0.76. The most frequent cause of bleeding were gastric and duodenal ulcers (55.4%); 278 patients (25.8%) received endoscopic treatment of which 69.1% had combined therapy. Rebleeding occurred in 36 patients (3.4%) of which 50% died. In-hospital mortality was 10.2%, of which only 3.1% was associated to bleeding. When comparing causes of death among patients with and without comorbidities, only hypovolemic shock was found significative (48.3 vs. 25%; p = 0.020). Binary logistic regression found that the number of comorbidities, Rockall scale score; serum albumin < 2.6 g/dL on admission; rebleeding and length of hospital stay were independent risk factors of in-hospital mortality.
the number of comorbidities, the Rockall scales core, an albumin level < 2.6 g/dL, the presence of rebleeding and hospital stay were predictors of in-hospital mortality in patients with NVUGB.</description><identifier>ISSN: 1130-0108</identifier><identifier>DOI: 10.4321/S1130-01082011000400005</identifier><identifier>PMID: 21526873</identifier><language>eng</language><publisher>Spain: Sociedad Española de Patología Digestiva</publisher><subject>Aged ; Cardiovascular Diseases - epidemiology ; Comorbidity ; Diabetes Mellitus - epidemiology ; Endoscopy, Digestive System ; Epinephrine - therapeutic use ; Female ; Gastroenterology & Hepatology ; Gastrointestinal Hemorrhage - etiology ; Gastrointestinal Hemorrhage - mortality ; Gastrointestinal Hemorrhage - therapy ; Geriatrics & Gerontology ; Hospital Mortality ; Humans ; Hypoalbuminemia - epidemiology ; Infectious Diseases ; Length of Stay ; Male ; Mexico - epidemiology ; Middle Aged ; Oncology ; Pathology ; Peptic Ulcer Hemorrhage - mortality ; Peptic Ulcer Hemorrhage - therapy ; Pharmacology & Pharmacy ; Prospective Studies ; Proton Pump Inhibitors - therapeutic use ; Radiology, Nuclear Medicine & Medical Imaging ; Recurrence ; Risk Factors ; Shock - etiology ; Shock - mortality ; Surgery</subject><ispartof>Revista española de enfermedades digestivas, 2011-04, Vol.103 (4), p.196-203</ispartof><rights>This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c454t-d20b604af8b176668497148fb59ffbdba3e0e18aa8ae2666013e9b63f66ff7573</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,864,885,27915,27916</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21526873$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>González-González, José Alberto</creatorcontrib><creatorcontrib>Vázquez-Elizondo, Genaro</creatorcontrib><creatorcontrib>García-Compeán, Diego</creatorcontrib><creatorcontrib>Gaytán-Torres, Juan Obed</creatorcontrib><creatorcontrib>Flores-Rendón, Ángel Ricardo</creatorcontrib><creatorcontrib>Jáquez-Quintana, Joel Omar</creatorcontrib><creatorcontrib>Garza-Galindo, Aldo Azael</creatorcontrib><creatorcontrib>Cárdenas-Sandoval, Martha Graciela</creatorcontrib><creatorcontrib>Maldonado-Garza, Héctor Jesús</creatorcontrib><title>Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding</title><title>Revista española de enfermedades digestivas</title><addtitle>Rev Esp Enferm Dig</addtitle><description>to determine the independent predictors of in-hospital death of Hispanic patients with nonvariceal upper gastrointestinal bleeding (NVUGB).
prospective and observational trial.
in a period between 2000 and 2009, all patients with NVUGB admitted to our hospital were studied. Demographical and clinical characteristics, endoscopic findings and laboratory tests were evaluated χ² and Mann-Whitney U analyses were per-formed for comparisons, and binary logistic regression was employed to identify independent predictors of in-hospital mortality.
1,067 patients were included, 65% male with a mean age of 58.8 years. Mean number of comorbidities per patient was 1.6 ± 0.76. The most frequent cause of bleeding were gastric and duodenal ulcers (55.4%); 278 patients (25.8%) received endoscopic treatment of which 69.1% had combined therapy. Rebleeding occurred in 36 patients (3.4%) of which 50% died. In-hospital mortality was 10.2%, of which only 3.1% was associated to bleeding. When comparing causes of death among patients with and without comorbidities, only hypovolemic shock was found significative (48.3 vs. 25%; p = 0.020). Binary logistic regression found that the number of comorbidities, Rockall scale score; serum albumin < 2.6 g/dL on admission; rebleeding and length of hospital stay were independent risk factors of in-hospital mortality.
the number of comorbidities, the Rockall scales core, an albumin level < 2.6 g/dL, the presence of rebleeding and hospital stay were predictors of in-hospital mortality in patients with NVUGB.</description><subject>Aged</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Comorbidity</subject><subject>Diabetes Mellitus - epidemiology</subject><subject>Endoscopy, Digestive System</subject><subject>Epinephrine - therapeutic use</subject><subject>Female</subject><subject>Gastroenterology & Hepatology</subject><subject>Gastrointestinal Hemorrhage - etiology</subject><subject>Gastrointestinal Hemorrhage - mortality</subject><subject>Gastrointestinal Hemorrhage - therapy</subject><subject>Geriatrics & Gerontology</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>Hypoalbuminemia - epidemiology</subject><subject>Infectious Diseases</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Mexico - epidemiology</subject><subject>Middle Aged</subject><subject>Oncology</subject><subject>Pathology</subject><subject>Peptic Ulcer Hemorrhage - mortality</subject><subject>Peptic Ulcer Hemorrhage - therapy</subject><subject>Pharmacology & Pharmacy</subject><subject>Prospective Studies</subject><subject>Proton Pump Inhibitors - therapeutic use</subject><subject>Radiology, Nuclear Medicine & Medical Imaging</subject><subject>Recurrence</subject><subject>Risk Factors</subject><subject>Shock - etiology</subject><subject>Shock - mortality</subject><subject>Surgery</subject><issn>1130-0108</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UctOwzAQ9AFES-EXIDdOKXbs2M4RVbykSiAB58hO7NZVYgfbAfXvMbT0gsRhNdLOzO5qB4BLBOcEF-j6BSEMc4ggLyBCEEKSCpZHYHogJuA0hE1iMC2LEzApUFlQzvAUiGevWtNE50PmdGZsvnZhMFF0We98AhO3qZsNIhplY8g-TVxn1tn8Q3jTqKQbh0H5bCVC9M7YqEI0NrVlp9JkuzoDx1p0QZ3vcQbe7m5fFw_58un-cXGzzBtSkpi3BZQUEqG5RIxSyknFEOFalpXWspUCK6gQF4ILVSQeIqwqSbGmVGtWMjwD893c0BjVuXrjRp_uCPXPf-o__0mGq51h8O59TGfXvQmN6jphlRtDzVlBcEUYSUq2UzbeheCVrgdveuG3NYL1dwb_7LjY7xhlr9qD7zcA_AVcK4K4</recordid><startdate>20110401</startdate><enddate>20110401</enddate><creator>González-González, José Alberto</creator><creator>Vázquez-Elizondo, Genaro</creator><creator>García-Compeán, Diego</creator><creator>Gaytán-Torres, Juan Obed</creator><creator>Flores-Rendón, Ángel Ricardo</creator><creator>Jáquez-Quintana, Joel Omar</creator><creator>Garza-Galindo, Aldo Azael</creator><creator>Cárdenas-Sandoval, Martha Graciela</creator><creator>Maldonado-Garza, Héctor Jesús</creator><general>Sociedad Española de Patología Digestiva</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>GPN</scope></search><sort><creationdate>20110401</creationdate><title>Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding</title><author>González-González, José Alberto ; Vázquez-Elizondo, Genaro ; García-Compeán, Diego ; Gaytán-Torres, Juan Obed ; Flores-Rendón, Ángel Ricardo ; Jáquez-Quintana, Joel Omar ; Garza-Galindo, Aldo Azael ; Cárdenas-Sandoval, Martha Graciela ; Maldonado-Garza, Héctor Jesús</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c454t-d20b604af8b176668497148fb59ffbdba3e0e18aa8ae2666013e9b63f66ff7573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Aged</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Comorbidity</topic><topic>Diabetes Mellitus - epidemiology</topic><topic>Endoscopy, Digestive System</topic><topic>Epinephrine - therapeutic use</topic><topic>Female</topic><topic>Gastroenterology & Hepatology</topic><topic>Gastrointestinal Hemorrhage - etiology</topic><topic>Gastrointestinal Hemorrhage - mortality</topic><topic>Gastrointestinal Hemorrhage - therapy</topic><topic>Geriatrics & Gerontology</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>Hypoalbuminemia - epidemiology</topic><topic>Infectious Diseases</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Mexico - epidemiology</topic><topic>Middle Aged</topic><topic>Oncology</topic><topic>Pathology</topic><topic>Peptic Ulcer Hemorrhage - mortality</topic><topic>Peptic Ulcer Hemorrhage - therapy</topic><topic>Pharmacology & Pharmacy</topic><topic>Prospective Studies</topic><topic>Proton Pump Inhibitors - therapeutic use</topic><topic>Radiology, Nuclear Medicine & Medical Imaging</topic><topic>Recurrence</topic><topic>Risk Factors</topic><topic>Shock - etiology</topic><topic>Shock - mortality</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>González-González, José Alberto</creatorcontrib><creatorcontrib>Vázquez-Elizondo, Genaro</creatorcontrib><creatorcontrib>García-Compeán, Diego</creatorcontrib><creatorcontrib>Gaytán-Torres, Juan Obed</creatorcontrib><creatorcontrib>Flores-Rendón, Ángel Ricardo</creatorcontrib><creatorcontrib>Jáquez-Quintana, Joel Omar</creatorcontrib><creatorcontrib>Garza-Galindo, Aldo Azael</creatorcontrib><creatorcontrib>Cárdenas-Sandoval, Martha Graciela</creatorcontrib><creatorcontrib>Maldonado-Garza, Héctor Jesús</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>SciELO</collection><jtitle>Revista española de enfermedades digestivas</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>González-González, José Alberto</au><au>Vázquez-Elizondo, Genaro</au><au>García-Compeán, Diego</au><au>Gaytán-Torres, Juan Obed</au><au>Flores-Rendón, Ángel Ricardo</au><au>Jáquez-Quintana, Joel Omar</au><au>Garza-Galindo, Aldo Azael</au><au>Cárdenas-Sandoval, Martha Graciela</au><au>Maldonado-Garza, Héctor Jesús</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding</atitle><jtitle>Revista española de enfermedades digestivas</jtitle><addtitle>Rev Esp Enferm Dig</addtitle><date>2011-04-01</date><risdate>2011</risdate><volume>103</volume><issue>4</issue><spage>196</spage><epage>203</epage><pages>196-203</pages><issn>1130-0108</issn><abstract>to determine the independent predictors of in-hospital death of Hispanic patients with nonvariceal upper gastrointestinal bleeding (NVUGB).
prospective and observational trial.
in a period between 2000 and 2009, all patients with NVUGB admitted to our hospital were studied. Demographical and clinical characteristics, endoscopic findings and laboratory tests were evaluated χ² and Mann-Whitney U analyses were per-formed for comparisons, and binary logistic regression was employed to identify independent predictors of in-hospital mortality.
1,067 patients were included, 65% male with a mean age of 58.8 years. Mean number of comorbidities per patient was 1.6 ± 0.76. The most frequent cause of bleeding were gastric and duodenal ulcers (55.4%); 278 patients (25.8%) received endoscopic treatment of which 69.1% had combined therapy. Rebleeding occurred in 36 patients (3.4%) of which 50% died. In-hospital mortality was 10.2%, of which only 3.1% was associated to bleeding. When comparing causes of death among patients with and without comorbidities, only hypovolemic shock was found significative (48.3 vs. 25%; p = 0.020). Binary logistic regression found that the number of comorbidities, Rockall scale score; serum albumin < 2.6 g/dL on admission; rebleeding and length of hospital stay were independent risk factors of in-hospital mortality.
the number of comorbidities, the Rockall scales core, an albumin level < 2.6 g/dL, the presence of rebleeding and hospital stay were predictors of in-hospital mortality in patients with NVUGB.</abstract><cop>Spain</cop><pub>Sociedad Española de Patología Digestiva</pub><pmid>21526873</pmid><doi>10.4321/S1130-01082011000400005</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Aged Cardiovascular Diseases - epidemiology Comorbidity Diabetes Mellitus - epidemiology Endoscopy, Digestive System Epinephrine - therapeutic use Female Gastroenterology & Hepatology Gastrointestinal Hemorrhage - etiology Gastrointestinal Hemorrhage - mortality Gastrointestinal Hemorrhage - therapy Geriatrics & Gerontology Hospital Mortality Humans Hypoalbuminemia - epidemiology Infectious Diseases Length of Stay Male Mexico - epidemiology Middle Aged Oncology Pathology Peptic Ulcer Hemorrhage - mortality Peptic Ulcer Hemorrhage - therapy Pharmacology & Pharmacy Prospective Studies Proton Pump Inhibitors - therapeutic use Radiology, Nuclear Medicine & Medical Imaging Recurrence Risk Factors Shock - etiology Shock - mortality Surgery |
| title | Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding |
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