THIN-LAYER CHROMATOGRAPHY ON REVERSED PHASE IN THE CHARACTERIZATION OF RETENTION BEHAVIOUR, LIPOPHILICITY, AND PHARMACOKINETICS OF CYANOACETAMIDE DERIVATIVES

ABSTRACT Biological activity of a molecule is closely related to its lipophilicity. This significant parameter was determined for a group of potentially bioactive N-(4-phenylmonosubstituted)-2-cyanoacetamides applying thin-layer chromatography on reversed phase (RP-TLC) in mixtures of water and two...

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Veröffentlicht in:	Journal of the Chilean Chemical Society 2020-03, Vol.65 (1), p.4654-4660
Hauptverfasser:	Apostolov, Suzana, Vastag, Gyöngyi, Matijević, Borko, Đaković-Sekulić, Tatjana, Marinković, Aleksandar
Format:	Artikel
Sprache:	eng ; por
Schlagworte:	CHEMISTRY, MULTIDISCIPLINARY
Online-Zugang:	Volltext
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