SYNTHESIS AND LEISHMANICIDAL ACTIVITY OF NEW BIS-ALKYLQUINOLINES

Bis-alkylquinolines 1-6 were synthetized via Williamson reaction between 8-hydroxyquinaldine with different É, ù-dihaloalkanes. Structures of all the products were elucidated by spectroscopic analysis. Cytotoxic and antileishmanial activities of synthesized compounds were determinated on U-937 cells...

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Veröffentlicht in:Journal of the Chilean Chemical Society 2013, Vol.58 (2), p.1709-1712
Hauptverfasser: CARDONA, WILSON, ARANGO, VICTOR, DOMÍNGUEZ, JORGE J, ROBLEDO, SARA M, MUÑOZ, DIANA L, FIGADERE, BRUNO, VELEZ, IVAN D, SÁEZ, JAIRO
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